Professor Mark Schembri
Professor
School of Chemistry and Molecular Biosciences
Professorial Research Fellow & Group Leader
Institute for Molecular Bioscience
Centre Director of Centre for Superbug Solutions
Centre for Superbug Solutions
+61 7 336 53306
Primary research interest
Bacterial pathogenesis
About me
I completed my PhD at Monash University and postdoctoral studies at the Technical University of Denmark. In 2001, I was awarded a Postdoctoral Fellowship from the Danish Natural Sciences Research Council and was subsequently appointed to Lecturer. I joined The University of Queensland in 2004 as a Senior Lecturer and was promoted to Reader in 2007 and to Professor in 2010. I was awarded an ARC Future Fellowship in 2011.
Research focus and collaborations
The common research theme in my laboratory is the study of surface proteins that mediate adhesion, aggregation and biofilm formation by bacterial pathogens. Adhesion is the primary mechanism by which bacteria colonize host tissue surfaces and initiate disease. My research deals primarily with pathogenic Escherichia coli that cause intestinal and extra-intestinal infections. A major focus is uropathogenic E. coli (including multidrug-resistant strains), where we study the role of adhesins and other surface components in the development of biofilms and colonisation of the urinary tract. Biofilms are microbial communities characterized by cells that are irreversibly attached to a substratum or interface or to each other. My laboratory also investigates mechanisms of adhesion and biofilm formation by other multidrug-resistant pathogens including Acinetobacter baumannii, Klebsiella pneumoniae and Enterobacter species.
Collaborations
International: A/Prof Jean-Marc Ghigo, Pasteur Institute, France. Prof Scott Hultgren, Washington University School of Medicine, St. Louis, USA. Prof Tim Walsh, University of Cardiff, UK. Prof Ian Henderson, University of Birmingham, UK. Dr Mathew Upton, Univerity of Manchester, UK. Prof Tim Ravasi, KAUST, Saudi Arabia.
National: Dr Scott Beatson (UQ), Prof Alastair McEwan (UQ), A/Prof Matthew Sweet (UQ), Prof David Paterson (UQ), Prof Jenny Martin (UQ), Dr Rowland Cobbold (UQ), Dr Glen Ulett (Griffith), Dr Begoña Heras (LaTrobe), Prof Kate Moore (UNSW), Dr Darren Trott (U Adel).
Group members
- Dr Timothy Kidd, NHMRC Early Career Fellow
- Dr Alvin Lo, Postdoctoral Research Fellow
Funded projects
- NHMRC Project Grant 2014-2017, Functional and genomic analysis of the globally disseminated multidrug-resistant Escherichia coli ST131 clone
Total value of grant: $793,056 - NHMRC Project Grant 2013-2015, Role of autotransporter proteins in uropathogenic E. coli infections (M.A. Schembri)
Total value of grant: $590,222 - NHMRC Project Grant 2012-2014, Evolution and pathogenicity of NDM-1 positive Escherichia coli (M.A. Schembri, T.R. Walsh, S.A. Beatson)
Total value of grant: $622,350 - NHMRC Project Grant 2011-2013, Role of macrophages in uropathogenic E. coli infections (M.A. Schembri, M.J. Sweet, G.C. Ulett, T. Ravassi)
Total value of grant: $555,048. - NHMRC Project Grant 2011-2013, Escherichia coli ST131: an emerging pathogen (M.A. Schembri, S.A. Beatson)
Total value of grant: $555,048 - NHMRC Project Grant 2010-2012, Adhesins of uropathogenic Escherichia coli (M.A. Schembri)
Total value of grant: $391,125 - ARC Discovery Project 2010-2012, Disulfide catalysis and protein folding in bacterial virulence (M.A .Schembri, A.G. McEwan, B. Heras)
Total value of grant: $300,000. - ARC Discovery Project 2010-2012, Autotransporter proteins of enterohemorrhagic Escherichia coli O157:H7 (M.A. Schembri)
Total value of grant: $300,000 - National and International Research Alliances Program 2009-2011, Development of a livestock vaccine to reduce food-borne enterohemorrhagic E. coli (EHEC) infections in humans (R Cobbold, W Jorgensen, MA Schembri, T Mahony)
Total value of grant: $2,000,000
Teaching interests
- MICR3001 Microbes & Human Health
Student supervision
PhD: Principal Advisor 6, Associate Advisor 2 Honours: 1
Achievements and awards
Professional activities
- Fellow of the Australian Society for Microbiology (FASM)
Researcher biography
Professor Mark Schembri is a prominent microbiologist with experience in combating the global health crisis presented by multi-drug resistant pathogens. Professor Schembri's expertise on the virulence of bacterial pathogens and his innovative analysis of biofilm formation aims to improve the outcomes of the >400 million individuals that suffer from urinary tract infections each year across the globe.
Through the application of genetic, genomic and functional studies on uropathogenic E. coli, Professor Schembri has identified targets to reduce the virulence of this pathogen, and will pursue the development of life-saving therapeutic and preventative advances with the assistance of NHMRC, MRFF and ARC grants. Professor Schembri has tracked the rapid emergence and global spread of a virulent, drug-resistant E. coli clone and used genome sequencing to understand its evolution and virulence.
Links: Professor Schembri collaborates with national and international research leaders, including in Denmark, where he was a lecturer. Professor Schembri has strong links with other international experts in his field, including at the Pasteur Institute and the Wellcome Trust Sanger Institute in Cambridge. His research collaborations also span lead groups at UQ and other top Australian institutes, including Griffith and La Trobe Universities.
Membership, Funding and patents: Since 2014, Professor Schembri has been awarded over $15 million in funding from competitive national research funding bodies. He holds provisional patents for the development of novel therapeutic agents and vaccine antigens. He is a Fellow of the American Academy of Microbiology, and is regularly invited to speak at international conferences in his field.
Awards and Communication: Professor Schembri was the recipient of the Frank Fenner Award (2010) and the ASM BacPath Oration Award (2019) for his outstanding original research contribution to the study of Infectious Disease. He was an Australian Research Council Future Fellow (2011-2015) a National Health and Medical Research Council Senior Research Fellow (2016-2020). Professor Schembri is the author of >240 peer-reviewed research manuscripts. He is President of the Australian Society for Microbiology (2022-2026).
Book Chapter
Ravasi, Timothy, Mavromatis, Charalampos (Harris), Bokil, Nilesh J., Schembri, Mark A. and Sweet, Matthew J. (2016). Co-transcriptomic analysis by RNA sequencing to simultaneously measure regulated gene expression in host and bacterial pathogen. Toll-like receptors: practice and methods. (pp. 145-158) edited by Claire E. McCoy. Heidelberg, Germany: Springer. doi: 10.1007/978-1-4939-3335-8_10
Journal Articles
Obonyo, Nchafatso G., Raman, Sainath, Suen, Jacky Y., Peters, Kate M., Phan, Minh-Duy, Passmore, Margaret R., Bouquet, Mahe, Wilson, Emily S., Hyslop, Kieran, Palmieri, Chiara, White, Nicole, Sato, Kei, Farah, Samia M., Gandini, Lucia, Liu, Keibun, Fior, Gabriele, Heinsar, Silver, Ijuin, Shinichi, Kyun Ro, Sun, Abbate, Gabriella, Ainola, Carmen, Sato, Noriko, Lundon, Brooke, Portatadino, Sofia, Rachakonda, Reema H., Schneider, Bailey, Harley, Amanda, See Hoe, Louise E., Schembri, Mark A. ... Fraser, John F. (2024). An ovine septic shock model of live bacterial infusion. Intensive Care Medicine Experimental, 12 (1) 94. doi: 10.1186/s40635-024-00684-x
Nhu, Nguyen Thi Khanh, Forde, Brian M., Ben Zakour, Nouri L., Phan, Minh-Duy, Roberts, Leah W., Beatson, Scott A. and Schembri, Mark A. (2024). Evolution of the pheV-tRNA integrated genomic island in Escherichia coli. PLoS Genetics, 20 (10) e1011459, e1011459. doi: 10.1371/journal.pgen.1011459
Graf, Fabrice E., Goodman, Richard N., Gallichan, Sarah, Forrest, Sally, Picton-Barlow, Esther, Fraser, Alice J., Phan, Minh-Duy, Mphasa, Madalitso, Hubbard, Alasdair T. M., Musicha, Patrick, Schembri, Mark A., Roberts, Adam P., Edwards, Thomas, Lewis, Joseph M. and Feasey, Nicholas A. (2024). Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales. Nature Communications, 15 (1) 9019, 1-12. doi: 10.1038/s41467-024-53391-2
White, Rhys T., Ashcroft, Melinda M., Bauer, Michelle J., Bell, Jan, Butkiewicz, Dominika, Álvarez-Fraga, Laura, Gibson, Justine S., Kidsley, Amanda K., Mollinger, Joanne L., Peters, Kate M., Phan, Minh-Duy, Roberts, Leah W., Rogers, Benjamin A., Schembri, Mark A., Trott, Darren J., Turnidge, John, Forde, Brian M. and Beatson, Scott A. (2024). The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen. Access Microbiology, 6 (10). doi: 10.1099/acmi.0.000894.v3
Chang, Chyden, Phan, Minh-Duy and Schembri, Mark A. (2024). Modified Tn
7
transposon vectors for controlled chromosomal gene expression. Applied and Environmental Microbiology, 90 (10) e01556-24, e0155624. doi: 10.1128/aem.01556-24
Asgharzadeh Kangachar, Shahla, Logel, Dominic Y., Trofimova, Ellina, Zhu, Hannah X., Zaugg, Julian, Schembri, Mark A., Weynberg, Karen D. and Jaschke, Paul R. (2024). Discovery and characterisation of new phage targeting uropathogenic Escherichia coli. Virology, 597 110148, 110148. doi: 10.1016/j.virol.2024.110148
Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Hancock, Steven J., Peters, Kate M., Alvarez-Fraga, Laura, Forde, Brian M., Andersen, Stacey B., Miliya, Thyl, Harris, Patrick N. A., Beatson, Scott A., Schlebusch, Sanmarie, Bergh, Haakon, Turner, Paul, Brauner, Annelie, Westerlund-Wikström, Benita, Irwin, Adam D. and Schembri, Mark A (2024). High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection. eLife, 12 ARTN RP91853. doi: 10.7554/elife.91853.3
Nhu, Nguyen Thi Khanh, Rahman, M. Arifur, Goh, Kelvin G. K., Kim, Seung Jae, Phan, Minh-Duy, Peters, Kate M., Alvarez-Fraga, Laura, Hancock, Steven J., Ravi, Chitra, Kidd, Timothy J., Sullivan, Matthew J., Irvine, Katharine M., Beatson, Scott A., Sweet, Matthew J., Irwin, Adam D., Vukovic, Jana, Ulett, Glen C., Hasnain, Sumaira Z. and Schembri, Mark A. (2024). A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria. Nature Communications, 15 (1) 1441, 1441. doi: 10.1038/s41467-024-45176-4
Das Gupta, Kaustav, Curson, James E. B., Tarique, Abdullah A., Kapetanovic, Ronan, Schembri, Mark A., Fantino, Emmanuelle, Sly, Peter D. and Sweet, Matthew J. (2024). CFTR is required for zinc-mediated antibacterial defense in human macrophages. Proceedings of the National Academy of Sciences, 121 (8) e2315190121, 1-11. doi: 10.1073/pnas.2315190121
Phan, Minh-Duy, Schirra, Horst Joachim, Nhu, Nguyen Thi Khanh, Peters, Kate M., Sarkar, Sohinee, Allsopp, Luke P., Achard, Maud E. S., Kappler, Ulrike and Schembri, Mark A. (2024). Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant
Escherichia coli
ST131. mBio, 15 (3), e0338823. doi: 10.1128/mbio.03388-23
Lian, Zheng Jie, Phan, Minh-Duy, Hancock, Steven J., Nhu, Nguyen Thi Khanh, Paterson, David L. and Schembri, Mark A. (2023). Genetic basis of I-complex plasmid stability and conjugation. PLoS Genetics, 19 (6) e1010773, 1-21. doi: 10.1371/journal.pgen.1010773
Nhu, Nguyen Thi Khanh, Ravi, Chitra and Schembri, Mark A. (2023). Uropathogenic Escherichia coli biofilms. Microbiology Australia, 44 (2), 109-112. doi: 10.1071/ma23030
Mu, Andre, Klare, William P., Baines, Sarah L., Ignatius Pang, C. N., Guérillot, Romain, Harbison-Price, Nichaela, Keller, Nadia, Wilksch, Jonathan, Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Keller, Bernhard, Nijagal, Brunda, Tull, Dedreia, Dayalan, Saravanan, Chua, Hwa Huat Charlie, Skoneczny, Dominik, Koval, Jason, Hachani, Abderrahman, Shah, Anup D., Neha, Nitika, Jadhav, Snehal, Partridge, Sally R., Cork, Amanda J., Peters, Kate, Bertolla, Olivia, Brouwer, Stephan, Hancock, Steven J., Álvarez-Fraga, Laura, De Oliveira, David M. P. ... Walker, Mark J. (2023). Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature Communications, 14 (1) 1530, 1-21. doi: 10.1038/s41467-023-37200-w
Wang, Yue, Yu, Zhigang, Ding, Pengbo, Lu, Ji, Mao, Likai, Ngiam, Lyman, Yuan, Zhiguo, Engelstädter, Jan, Schembri, Mark A. and Guo, Jianhua (2023). Antidepressants can induce mutation and enhance persistence toward multiple antibiotics. Proceedings of the National Academy of Sciences, 120 (5) e2208344120, 1-12. doi: 10.1073/pnas.2208344120
Das Gupta, Kaustav, Ramnath, Divya, von Pein, Jessica B., Curson, James E. B., Wang, Yizhuo, Abrol, Rishika, Kakkanat, Asha, Moradi, Shayli Varasteh, Gunther, Kimberley S., Murthy, Ambika M. V., Stocks, Claudia J., Kapetanovic, Ronan, Reid, Robert C., Iyer, Abishek, Ilka, Zoe C., Nauseef, William M., Plan, Manuel, Luo, Lin, Stow, Jennifer L., Schroder, Kate, Karunakaran, Denuja, Alexandrov, Kirill, Shakespear, Melanie R., Schembri, Mark A., Fairlie, David P. and Sweet, Matthew J. (2023). HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences, 120 (4) e2212813120, 1-12. doi: 10.1073/pnas.2212813120
O’Boyle, Nicky, Douce, Gillian R., Farrell, Gillian, Rattray, Nicholas J. W., Schembri, Mark A., Roe, Andrew J. and Connolly, James P. R. (2022). Distinct ecological fitness factors coordinated by a conserved Escherichia coli regulator during systemic bloodstream infection. Proceedings of the National Academy of Sciences, 120 (1) e2212175120, 1-10. doi: 10.1073/pnas.2212175120
Boittier, Eric D., Wimmer, Norbert, Harris, Alexandria K., Schembri, Mark A. and Ferro, Vito (2022). Synthesis of a Gal-β-(1→4)-Gal disaccharide as a ligand for the fimbrial adhesin UcaD. Australian Journal of Chemistry, 76 (1), 30-36. doi: 10.1071/ch22158
Ding, Pengbo, Lu, Ji, Wang, Yue, Schembri, Mark A. and Guo, Jianhua (2022). Antidepressants promote the spread of antibiotic resistance via horizontally conjugative gene transfer. Environmental Microbiology, 24 (11), 5261-5276. doi: 10.1111/1462-2920.16165
Manik, Mohammad K., Shi, Yun, Li, Sulin, Zaydman, Mark A., Damaraju, Neha, Eastman, Samuel, Smith, Thomas G., Gu, Weixi, Masic, Veronika, Mosaiab, Tamim, Weagley, James S., Hancock, Steven J., Vasquez, Eduardo, Hartley-Tassell, Lauren, Kargios, Nestoras, Maruta, Natsumi, Lim, Bryan Y. J., Burdett, Hayden, Landsberg, Michael J., Schembri, Mark A., Prokes, Ivan, Song, Lijiang, Grant, Murray, DiAntonio, Aaron, Nanson, Jeffrey D., Guo, Ming, Milbrandt, Jeffrey, Ve, Thomas and Kobe, Bostjan (2022). Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science, 377 (6614) eadc8969, 1-11. doi: 10.1126/science.adc8969
Lv, You, Zheng, Shan, Goldenzweig, Adi, Liu, Fengjiang, Gao, Yan, Yang, Xiuna, Kandale, Ajit, McGeary, Ross P., Williams, Simon, Kobe, Bostjan, Schembri, Mark A., Landsberg, Michael J., Wu, Bin, Brück, Thomas B., Sieber, Volker, Boden, Mikael, Rao, Zihe, Fleishman, Sarel J., Schenk, Gerhard and Guddat, Luke W. (2022). Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals. Applied Biosciences, 1 (2), 163-178. doi: 10.3390/applbiosci1020011
Hancock, Steven J., Lo, Alvin W., Ve, Thomas, Day, Christopher J., Tan, Lendl, Mendez, Alejandra A., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Peters, Kate M., Richards, Amanda C., Fleming, Brittany A., Chang, Chyden, Ngu, Dalton H. Y., Forde, Brian M., Haselhorst, Thomas, Goh, Kelvin G. K., Beatson, Scott A., Jennings, Michael P., Mulvey, Matthew A., Kobe, Bostjan and Schembri, Mark A. (2022). Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. PLoS Pathogens , 18 (6) e1010582, e1010582. doi: 10.1371/journal.ppat.1010582
Schembri, Mark A., Nhu, Nguyen Thi Khanh and Phan, Minh-Duy (2022). Gut–bladder axis in recurrent UTI. Nature Microbiology, 7 (5), 601-602. doi: 10.1038/s41564-022-01113-z
Vo, Julieanne L., Ortiz, Gabriela C. Martínez, Totsika, Makrina, Lo, Alvin W., Hancock, Steven J., Whitten, Andrew E., Hor, Lilian, Peters, Kate M., Ageorges, Valentin, Caccia, Nelly, Desvaux, Mickaël, Schembri, Mark A., Paxman, Jason J. and Heras, Begoña (2022). Variation of Antigen 43 self-association modulates bacterial compacting within aggregates and biofilms. npj Biofilms and Microbiomes, 8 (1) 20, 20. doi: 10.1038/s41522-022-00284-1
Phan, Minh-Duy, Peters, Kate M., Alvarez Fraga, Laura, Wallis, Steven C., Hancock, Steven, Nhu, Nguyen Thi Khanh, Forde, Brian, Bauer, Michelle J., Paterson, David L., Beatson, Scott A, Lipman, Jeffrey and Schembri, Mark A. (2022). Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 66 (1) e02146-21, 1-11. doi: 10.1128/aac.02146-21
Alvarez-Fraga, Laura, Phan, Minh-Duy, Goh, Kelvin G. K., Nhu, Nguyen Thi Khanh, Hancock, Steven J., Allsopp, Luke P., Peters, Kate M., Forde, Brian M., Roberts, Leah W., Sullivan, Matthew J., Totsika, Makrina, Beatson, Scott A., Ulett, Glen C. and Schembri, Mark A. (2022). Differential Afa/Dr fimbriae expression in the multidrug-resistant Escherichia coli ST131 clone. mBio, 13 (1) e03519, e0351921. doi: 10.1128/mbio.03519-21
De Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721. doi: 10.1128/mbio.03517-21
Amiss, Anna S., von Pein, Jessica B., Webb, Jessica R., Condon, Nicholas D., Harvey, Peta J., Phan, Minh-Duy, Schembri, Mark A., Currie, Bart J., Sweet, Matthew J., Craik, David J., Kapetanovic, Ronan, Henriques, Sónia Troeira and Lawrence, Nicole (2021). Modified horseshoe crab peptides target and kill bacteria inside host cells. Cellular and Molecular Life Sciences, 79 (1) 38, 38. doi: 10.1007/s00018-021-04041-z
De Silva, April P., Schembri, Mark A., Sarah, Angus H., Chao, Jessica, Yip, Kwok Ho, Cildir, Gökhan, Lopez, Angel, Tumes, Damon J. and Pant, Harshita (2021). Short-term oral steroids significantly improves chronic rhinosinusitis without nasal polyps. Laryngoscope, 131 (10), E2618-E2626. doi: 10.1002/lary.29495
da Silva, Patrick, Lustri, Bruna C., Castilho, Ivana Giovannetti, Ferreira, Adriano Martison, Hernandes, Rodrigo T., Schembri, Mark A. and Moreira, Cristiano G. (2021). Genome profiling of fluoroquinolone-resistant uropathogenic Escherichia coli isolates from Brazil. Brazilian Journal of Microbiology, 52 (3), 1067-1075. doi: 10.1007/s42770-021-00513-3
Ngiam, Lyman, Schembri, Mark A., Weynberg, Karen and Guo, Jianhua (2021). Bacteriophage isolated from non‐target bacteria demonstrates broad host range infectivity against multidrug resistant bacteria. Environmental Microbiology, 23 (9) 1462-2920.15714, 1-18. doi: 10.1111/1462-2920.15714
Hancock, Steven J., Phan, Minh‐Duy, Roberts, Leah, Vu, Thu Ngoc Minh, Harris, Patrick N.A., Beatson, Scott A. and Schembri, Mark A. (2021). Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component. Molecular Microbiology, 116 (1), 154-167. doi: 10.1111/mmi.14697
Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction. BMC Genomics, 22 (1) 474, 474. doi: 10.1186/s12864-021-07767-z
Day, Christopher J., Lo, Alvin W., Hartley-Tassell, Lauren E., Argente, M. Pilar, Poole, Jessica, King, Nathan P., Tiralongo, Joe, Jennings, Michael P. and Schembri, Mark A. (2021). Discovery of bacterial fimbria–glycan interactions using whole-cell recombinant Escherichia coli expression. mBio, 12 (1) e03664-20, 1-10. doi: 10.1128/mbio.03664-20
Roberts, Leah W., Forde, Brian M., Hurst, Trish, Ling, Weiping, Nimmo, Graeme R., Bergh, Haakon, George, Narelle, Hajkowicz, Krispin, McNamara, John F., Lipman, Jeffrey, Permana, Budi, Schembri, Mark A., Paterson, David, Beatson, Scott A. and Harris, Patrick N. A. (2021). Genomic surveillance, characterization and intervention of a polymicrobial multidrug-resistant outbreak in critical care. Microbial Genomics, 7 (3) 000530. doi: 10.1099/mgen.0.000530
Pein, Jessica B., Stocks, Claudia J., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2021). An alloy of zinc and innate immunity: galvanizing host defence against infection. Cellular Microbiology, 23 (1) e13268, 1-11. doi: 10.1111/cmi.13268
De Oliveira, David M. P., Bohlmann, Lisa, Conroy, Trent, Jen, Freda E.-C., Everest-Dass, Arun, Hansford, Karl A., Bolisetti, Raghu, El-Deeb, Ibrahim M., Forde, Brian M., Phan, Minh-Duy, Lacey, Jake A., Tan, Aimee, Rivera-Hernandez, Tania, Brouwer, Stephan, Keller, Nadia, Kidd, Timothy J., Cork, Amanda J., Bauer, Michelle J., Cook, Gregory M., Davies, Mark R., Beatson, Scott A., Paterson, David L., McEwan, Alastair G., Li, Jian, Schembri, Mark A., Blaskovich, Mark A. T., Jennings, Michael P., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2020). Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translational Medicine, 12 (570) abb3791, eabb3791. doi: 10.1126/scitranslmed.abb3791
Chamoun, Michelle N., Sullivan, Matthew J., Goh, Kelvin G. K., Acharya, Dhruba, Ipe, Deepak S., Katupitiya, Lahiru, Gosling, Dean, Peters, Kate M., Sweet, Matthew J., Sester, David P., Schembri, Mark A. and Ulett, Glen C. (2020). Restriction of chronic Escherichia coli urinary tract infection depends upon T cell-derived interleukin-17, a deficiency of which predisposes to flagella-driven bacterial persistence. FASEB Journal, 34 (11), 14572-14587. doi: 10.1096/fj.202000760R
Armstrong, Declan J., Nieminen, Timo A., Favre-Bulle, Itia, Stilgoe, Alexander B., Lenton, Isaac C. D., Schembri, Mark A. and Rubinsztein-Dunlop, Halina (2020). Optical force measurements illuminate dynamics of Escherichia coli in viscous media. Frontiers in Physics, 8 575732. doi: 10.3389/fphy.2020.575732
Kidsley, Amanda K., White, Rhys T., Beatson, Scott A., Saputra, Sugiyono, Schembri, Mark A., Gordon, David, Johnson, James R., O’Dea, Mark, Mollinger, Joanne L., Abraham, Sam and Trott, Darren J. (2020). Companion animals are spillover hosts of the multidrug-resistant human extraintestinal Escherichia coli pandemic clones ST131 and ST1193. Frontiers in Microbiology, 11 1968, 1968. doi: 10.3389/fmicb.2020.01968
Hancock, Steven J., Phan, Minh-Duy, Luo, Zhenyao, Lo, Alvin W., Peters, Kate M., Nhu, Nguyen Thi Khanh, Forde, Brian M., Whitfield, Jason, Yang, Ji, Strugnell, Richard A., Paterson, David L., Walsh, Timothy R., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2020). Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nature Microbiology, 5 (11), 1340-1348. doi: 10.1038/s41564-020-0775-0
De Oliveira, David M. P., Forde, Brian M., Kidd, Timothy J., Harris, Patrick N. A., Schembri, Mark A., Beatson, Scott A., Paterson, David L. and Walker, Mark J. (2020). Antimicrobial resistance in ESKAPE pathogens. Clinical Microbiology Reviews, 33 (3) e00181-19, e00181-19. doi: 10.1128/cmr.00181-19
Stocks, Claudia J., Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2020). Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli. Journal of Leukocyte Biology, 109 (2) JLB.2HI0420-160R, 287-297. doi: 10.1002/jlb.2hi0420-160r
Stewart, Adam G., Harris, Patrick N. A., Henderson, Andrew, Schembri, Mark A. and Paterson, David L. (2020). Oral cephalosporin and β-lactamase inhibitor combinations for ESBL-producing Enterobacteriaceae urinary tract infections. Journal of Antimicrobial Chemotherapy, 75 (9), 2384-2393. doi: 10.1093/jac/dkaa183
Phan, Minh-Duy, Bottomley, Amy L., Peters, Kate M., Harry, Elizabeth J. and Schembri, Mark A. (2020). Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 75 (6), 1415-1423. doi: 10.1093/jac/dkaa023
Yip, Kwok Ho, Wilson, Nicholas J., Pant, Harshita, Brown, Christopher L., Busfield, Samantha, Ng, Milica, Alhamdoosh, Monther, Woodman, Naomi, Schembri, Mark, Tumes, Damon J., Vairo, Gino, Lopez, Angel F., Nash, Andrew D., Wilson, Michael J., Grimbaldeston, Michele A. and Owczarek, Catherine M. (2020). Anti-βc mAb CSL311 inhibits human nasal polyp pathophysiology in a humanized mouse xenograft model. Allergy: European Journal of Allergy and Clinical Immunology, 75 (2), 475-478. doi: 10.1111/all.14041
Roberts, Leah W., Harris, Patrick N. A., Forde, Brian M., Ben Zakour, Nouri L., Catchpoole, Elizabeth, Stanton-Cook, Mitchell, Phan, Minh-Duy, Sidjabat, Hanna E., Bergh, Haakon, Heney, Claire, Gawthorne, Jayde A., Lipman, Jeffrey, Allworth, Anthony, Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Schembri, Mark A., Paterson, David L. and Beatson, Scott A. (2020). Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei. Nature Communications, 11 (1) 466, 466. doi: 10.1038/s41467-019-14139-5
Roberts, Leah W., Catchpoole, Elizabeth, Jennison, Amy V., Bergh, Haakon, Hume, Anna, Heney, Claire, George, Narelle, Paterson, David L., Schembri, Mark A., Beatson, Scott A. and Harris, Patrick N. A. (2019). Genomic analysis of carbapenemase-producing Enterobacteriaceae in Queensland reveals widespread transmission of blaIMP-4 on an IncHI2 plasmid. Microbial Genomics, 6 (1) 000321. doi: 10.1099/mgen.0.000321
Acharya, Dhruba, Sullivan, Matthew J., Duell, Benjamin L., Goh, Kelvin G. K., Katupitiya, Lahiru, Gosling, Dean, Chamoun, Michelle N., Kakkanat, Asha, Chattopadhyay, Debasish, Crowley, Michael, Crossman, David K., Schembri, Mark A. and Ulett, Glen C. (2019). Rapid bladder interleukin-10 synthesis in response to uropathogenic Escherichia coli is part of a defense strategy triggered by the major bacterial flagellar filament FliC and contingent on TLR5. mSphere, 4 (6) e00545, e00545-19. doi: 10.1128/msphere.00545-19
Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Forde, Brian M., Murthy, Ambika M. V., Peters, Kate M., Day, Christopher J., Poole, Jessica, Kidd, Timothy J., Welch, Rodney A., Jennings, Michael P., Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2019). Complex multilevel control of hemolysin production by uropathogenic Escherichia coli. mBio, 10 (5) e02248-19. doi: 10.1128/mbio.02248-19
Goh, Kelvin G. K., Moriel, Danilo G., Hancock, Steven J., Phan, Minh-Duy and Schembri, Mark A. (2019). Bioinformatic and molecular analysis of inverse autotransporters from Escherichia coli. MSphere, 4 (4) e00572-19. doi: 10.1128/msphere.00572-19
Forde, Brian M., Roberts, Leah W., Phan, Minh-Duy, Peters, Kate M., Fleming, Brittany A., Russell, Colin W., Lenherr, Sara M., Myers, Jeremy B., Barker, Adam P., Fisher, Mark A., Chong, Teik-Min, Yin, Wai-Fong, Chan, Kok-Gan, Schembri, Mark A., Mulvey, Matthew A. and Beatson, Scott A. (2019). Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection. Nature Communications, 10 (1) 3643, 3643. doi: 10.1038/s41467-019-11571-5
Serafini, Agnese, Tan, Lendl, Horswell, Stuart, Howell, Steven, Greenwood, Daniel J., Hunt, Deborah M., Phan, Minh-Duy, Schembri, Mark, Monteleone, Mercedes, Montague, Christine R., Britton, Warwick, Garza-Garcia, Acely, Snijders, Ambrosius P., VanderVen, Brian, Gutierrez, Maximiliano G., West, Nicholas P. and de Carvalho, Luiz Pedro S. (2019). Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism. Molecular Microbiology, 112 (4) mmi.14362, 1284-1307. doi: 10.1111/mmi.14362
Paxman, Jason J., Lo, Alvin W., Sullivan, Matthew J., Panjikar, Santosh, Kuiper, Michael, Whitten, Andrew E., Wang, Geqing, Luan, Chi-Hao, Moriel, Danilo G., Tan, Lendl, Peters, Kate M., Phan, Minh-Duy, Gee, Christine L., Ulett, Glen C., Schembri, Mark A. and Heras, Begoña (2019). Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules. Nature Communications, 10 (1) 1967, 1967. doi: 10.1038/s41467-019-09814-6
Acharya, Dhruba, Sullivan, Matthew J., Duell, Benjamin L., Eveno, Tanguy, Schembri, Mark A. and Ulett, Glen C. (2019). Physical extraction and fast protein liquid chromatography for purifying flagella filament from uropathogenic Escherichia coli for immune assay. Frontiers in Cellular and Infection Microbiology, 9 (APR) 118, 118. doi: 10.3389/fcimb.2019.00118
Stocks, Claudia J., Phan, Minh-Duy, Achard, Maud E. S., Nhu, Nguyen Thi Khanh, Condon, Nicholas D., Gawthorne, Jayde A., Lo, Alvin W., Peters, Kate M., McEwan, Alastair G., Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2019). Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination. Proceedings of the National Academy of Sciences, 116 (13), 6341-6350. doi: 10.1073/pnas.1820870116
Murthy, Ambika M. V., Sullivan, Matthew J., Nhu, Nguyen Thi Khanh, Lo, Alvin W., Phan, Minh-Duy, Peters, Kate M., Boucher, Dave, Schroder, Kate, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), fj201802100R-7450. doi: 10.1096/fj.201802100R
Furlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begona, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A. and Martin, Jennifer L. (2019). Author correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance (vol 8, 16065, 2017). Nature Communications, 10 (1) 976, 976. doi: 10.1038/s41467-019-08920-9
McGregor, Ross E., Buffa, Eugene A., Tan, Christopher J., Schembri, Mark A., Badcock, Caro-Anne and Lai, Alen (2019). A Retrospective Study Using the String of Pearls Tibial Plateau Levelling Osteotomy Locking Plate for the Treatment of Cranial Cruciate Ligament Disease. Veterinary and Comparative Orthopaedics and Traumatology, 32 (6), 483-491. doi: 10.1055/s-0039-1692189
Chen, Weiyu, Zuo, Huali, Rolfe, Barbara, Schembri, Mark A., Cobbold, Rowland N., Zhang, Bing, Mahony, Timothy J. and Xu, Zhi Ping (2018). Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli. Journal of Controlled Release, 292, 196-209. doi: 10.1016/j.jconrel.2018.11.008
Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18. doi: 10.1128/mbio.02391-18
Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18, 1-12. doi: 10.1128/mBio.02391-18
Forde, Brian M., Zowawi, Hosam M., Harris, Patrick N. A., Roberts, Leah, Ibrahim, Emad, Shaikh, Nissar, Deshmukh, Anand, Sid Ahmed, Mazen A., Al Maslamani, Muna, Cottrell, Kyra, Trembizki, Ella, Sundac, Lana, Yu, Heidi H., Li, Jian, Schembri, Mark A., Whiley, David M., Paterson, David L. and Beatson, Scott A. (2018). Discovery of mcr-1-mediated colistin resistance in a highly virulent Escherichia coli lineage. mSphere, 3 (5) e00486-18. doi: 10.1128/msphere.00486-18
Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Lo, Alvin W., Forde, Brian M., Min Chong, Teik, Yin, Wai-Fong, Chan, Kok-Gan, Chromek, Milan, Brauner, Annelie, Chapman, Matthew R., Beatson, Scott A. and Schembri, Mark A. (2018). Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage. mBio, 9 (4) e01462-18. doi: 10.1128/mbio.01462-18
Battaglioli, E. J., Goh, K. G. K., Atruktsang, T. S., Schwartz, K., Schembri, M. A. and Welch, R. A. (2018). Identification and characterization of a phase-variable element that regulates the autotransporter UpaE in uropathogenic Escherichia coli. mBio, 9 (4) e01360-18. doi: 10.1128/mbio.01360-18
Coggon, Carrie F., Jiang, Andrew, Goh, Kelvin G. K., Henderson, Ian R., Schembri, Mark A. and Wells, Timothy J. (2018). A novel method of serum resistance by Escherichia coli that causes urosepsis. mBio, 9 (3) e00920-18, e00920-18. doi: 10.1128/mbio.00920-18
Chen, Zhuoran, Phan, Minh-Duy, Bates, Lucy J., Peters, Kate M., Mukerjee, Chinmoy, Moore, Kate H. and Schembri, Mark A. (2018). The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection. International Urogynecology Journal, 29 (12), 1-8. doi: 10.1007/s00192-018-3679-2
Murthy, Ambika M. V., Phan, Minh-Duy, Peters, Kate M., Nhu, Nguyen Thi Khanh, Welch, Rodney A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2018). Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages. Virulence, 9 (1), 1-32. doi: 10.1080/21505594.2018.1465786
Yuan, Xiaojun, Johnson, Matthew D., Zhang, Jing, Lo, Alvin W., Schembri, Mark A., Wijeyewickrema, Lakshmi C., Pike, Robert N., Huysmans, Gerard H. M., Henderson, Ian R. and Leyton, Denisse L. (2018). Molecular basis for the folding of β-helical autotransporter passenger domains. Nature Communications, 9 (1) 1395, 1395. doi: 10.1038/s41467-018-03593-2
Sarkar, Sohinee, Hutton, Melanie L., Vagenas, Dimitrios, Ruter, Rinaldo, Schüller, Stephanie, Lyras, Dena, Schembri, Mark A. and Totsika, Makrina (2018). Intestinal colonization traits of pandemic multidrug-resistant Escherichia coli ST131. The Journal of Infectious Diseases, 218 (6), 979-990. doi: 10.1093/infdis/jiy031
Djoko, Karrera Y., Achard, Maud E. S., Phan, Minh-Duy, Lo, Alvin W., Miraula, Manfredi, Prombhul, Sasiprapa, Hancock, Steven J., Peters, Kate M., Sidjabat, Hanna E., Harris, Patrick N., Mitić, Nataša, Walsh, Timothy R., Anderson, Gregory J., Shafer, William M., Paterson, David L., Schenk, Gerhard, McEwan, Alastair G. and Schembri, Mark A. (2018). Copper ions and coordination complexes as novel carbapenem adjuvants. Antimicrobial Agents and Chemotherapy, 62 (2) e02280-17. doi: 10.1128/AAC.02280-17
Chamoun, Michelle N., Blumenthal, Antje, Sullivan, Matthew J., Schembri, Mark A. and Ulett, Glen C. (2018). Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection. Critical Reviews in Microbiology, 44 (4), 1-22. doi: 10.1080/1040841X.2018.1426556
Stocks, Claudia J., Schembri, Mark A., Sweet, Matthew J. and Kapetanovic, Ronan (2018). For when bacterial infections persist: toll-like receptor-inducible direct antimicrobial pathways in macrophages. Journal of Leukocyte Biology, 103 (1), 35-51. doi: 10.1002/JLB.4RI0917-358R
Patel, Khushboo, Teran, David, Zheng, Shan, Kandale, Ajit, Garcia, Mario, Lv, You, Schembri, Mark A, McGeary, Ross P, Schenk, Gerhard and Guddat, Luke William (2017). Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity. Chemistry- A European Journal, 23 (72), 18289-18295. doi: 10.1002/chem.201704481
Harris, Patrick N. A., Ben Zakour, Nouri L., Roberts, Leah W., Wailan, Alexander M., Zowawi, Hosam M., Tambyah, Paul A., Lye, David C., Jureen, Roland, Lee, Tau H., Yin, Mo, Izharuddin, Ezlyn, Looke, David, Runnegar, Naomi, Rogers, Benjamin, Bhally, Hasan, Crowe, Amy, Schembri, Mark A., Beatson, Scott A. and Paterson, David L. (2017). Whole genome analysis of cephalosporin-resistant Escherichia coli from bloodstream infections in Australia, New Zealand and Singapore: high prevalence of CMY-2 producers and ST131 carrying blaCTX-M-15 and blaCTX-M-27. The Journal of Antimicrobial Chemotherapy, 73 (3), 634-642. doi: 10.1093/jac/dkx466
Goh, Kelvin G. K., Phan, Minh-Duy, Forde, Brian M., Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2017). Genome-wide discovery of genes required for capsule production by uropathogenic Escherichia coli. MBio, 8 (5) e01558-17. doi: 10.1128/mBio.01558-17
Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Achard, Maud E. S., Forde, Brian M., Hong, Kar Wai, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, West, Nicholas P., Walker, Mark J., Paterson, David L., Beatson, Scott A. and Schembri, Mark A. (2017). Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 72 (10), 2729-2736. doi: 10.1093/jac/dkx204
Martinez-Gil, Marta, Goh, Kelvin G. K., Rackaityte, Elze, Sakamoto, Chizuko, Audrain, Bianca, Moriel, Danilo G., Totsika, Makrina, Ghigo, Jean-Marc, Schembri, Mark A. and Beloin, Christophe (2017). YeeJ is an inverse autotransporter from Escherichia coli that binds to peptidoglycan and promotes biofilm formation. Scientific Reports, 7 (1) 11326, 11326. doi: 10.1038/s41598-017-10902-0
Furlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begona, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A. and Martin, Jennifer L. (2017). A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance. Nature Communications, 8 (1) 16065, 16065. doi: 10.1038/ncomms16065
Littler, Dene R., Ang, Sheng Y., Moriel, Danilo G., Kocan, Martina, Kleifeld, Oded, Johnson, Matthew D., Tran, Mai T., Paton, Adrienne W., Paton, James C., Summers, Roger J., Schembri, Mark A., Rossjohn, Jamie and Beddoe, Travis (2017). Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins. Journal of Biological Chemistry, 292 (36), 15143-15158. doi: 10.1074/jbc.M117.796094
Djoko, Karrera Y., Phan, Minh-Duy, Peters, Kate M., Walker, Mark J. , Schembri, Mark A. and McEwan, Alastair G. (2017). Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America, 114 (26), 6818-6823. doi: 10.1073/pnas.1620232114
Lo, Alvin W., Moriel, Danilo G., Phan, Minh-Duy, Schulz, Benjamin L., Kidd, Timothy J., Beatson, Scott A. and Schembri, Mark A. (2017). 'Omic' approaches to study Uropathogenic Escherichia coli virulence. Trends in Microbiology, 25 (9), 729-740. doi: 10.1016/j.tim.2017.04.006
Kakkanat, Asha, Minh-Duy Phan, Lo, Alvin W., Beatson, Scott A. and Schembri, Mark A. (2017). Novel genes associated with enhanced motility of Escherichia coli ST131. PLoS One, 12 (5) e0176290, e0176290.1-e0176290.22. doi: 10.1371/journal.pone.0176290
Hancock, Steven J., Phan, Minh-Duy, Peters, Kate M., Forde, Brian M., Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Paterson, David L., Walsh, Timothy R., Beatson, Scott A. and Schembri, Mark A. (2017). Identification of IncA/C plasmid replication and maintenance genes and development of a plasmid multi-locus sequence-typing scheme. Antimicrobial Agents and Chemotherapy, 61 (2) e01740. doi: 10.1128/AAC.01740-16
Ulett, Glen C. and Schembri, Mark A. (2016). Remodelling recurrent infection. Nature Microbiology, 2 (16256) 16256, 1-2. doi: 10.1038/nmicrobiol.2016.256
Moriel, Danilo G., Tan, Lendl, Goh, Kelvin G. K., Phan, Minh-Duy, Ipe, Deepak S., Lo, Alvin W., Peters, Kate M., Ulett, Glen C., Beatson, Scott. A. and Schembri, Mark A. (2016). A novel protective vaccine antigen from the core Escherichia coli genome. mSphere, 1 (6) e00326-16. doi: 10.1128/mSphere.00326-16
Shepherd, Mark, Achard, Maud E. S., Idris, Adi, Totsika, Makrina, Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Ribeiro, Cláudia A., Holyoake, Louise V., Ladakis, Dimitrios, Ulett, Glen C., Sweet, Matthew J., Poole, Robert K., McEwan, Alastair G. and Schembri, Mark A. (2016). The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection. Scientific Reports, 6 (1) 35285, 35285. doi: 10.1038/srep35285
Tan, Lendl, Moriel, Danilo G., Totsika, Makrina, Beatson, Scott A. and Schembri, Mark A. (2016). Differential regulation of the surface-exposed and secreted SslE lipoprotein in extraintestinal pathogenic Escherichia coli. PLoS One, 11 (9) e0162391, e0162391. doi: 10.1371/journal.pone.0162391
Sarkar, Sohinee, Roberts, Leah W., Phan, Minh-Duy, Tan, Lendl, Lo, Alvin W., Peters, Kate M., Paterson, David L., Upton, Mathew, Ulett, Glen C., Beatson, Scott A., Totsika, Makrina and Schembri, Mark A. (2016). Comprehensive analysis of type 1 fimbriae regulation in fimB-null strains from the multidrug resistant Escherichia coli ST131 clone. Molecular Microbiology, 101 (6), 1069-1087. doi: 10.1111/mmi.13442
Cheng, Ying, Chen, Zhouran, Gawthorne, Jayde A., Mukerjee, Chinmoy, Varettas, Kerry, Mansfield, Kylie J., Schembri, Mark A. and Moore, Kate H. (2016). Detection of intracellular bacteria in exfoliated urothelial cells from women with urge incontinence. Pathogens and Disease, 74 (7) ftw067, ftw067. doi: 10.1093/femspd/ftw067
Wailan, Alexander M., Sidjabat, Hanna E., Yam, Wan Keat, Alikhan, Nabil-Fareed, Petty, Nicola K., Sartor, Anna L., Williamson, Deborah A., Forde, Brian M., Schembri, Mark A., Beatson, Scott A., Paterson, David L., Walsh, Timothy R. and Partridge, Sally R. (2016). Mechanisms involved in acquisition of blaNDM genes by IncA/C2 and IncFIIY plasmids. Antimicrobial Agents and Chemotherapy, 60 (7), 4082-4088. doi: 10.1128/AAC.00368-16
Ben Zakour, Nouri L, Alsheikh-Hussain, Areej S, Ashcroft, Melinda M, Khanh Nhu, Nguyen Thi, Roberts, Leah W, Stanton-Cook, Mitchell, Schembri, Mark A and Beatson, Scott A (2016). Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131. mBio, 7 (3), 1-1. doi: 10.1128/mBio.00958-16
Stubenrauch, Christopher, Belousoff, Matthew J., Hay, Iain D., Shen, Hsin-Hui, Lillington, James, Tuck, Kellie L., Peters, Kate M., Phan, Minh-Duy, Lo, Alvin, W., Schembri, Mark A., Strugnell, Richard A., Waksman, Gabriel and Lithgow, Trevor (2016). Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine. Nature Microbiology, 1 (7) 16064, 16064. doi: 10.1038/nmicrobiol.2016.64
Nichols, Katie B., Totsika, Makrina, Moriel, Danilo G., Lo, Alvin W., Yang, Ji, Wurpel, Daniel J., Rossiter, Amanda E., Strugnell, Richard A., Henderson, Ian R., Ulett, Glen C., Beatson, Scott A. and Schembri, Mark A. (2016). Molecular characterisation of the Vacuolating Autotransporter Toxin in Uropathogenic Escherichia coli. Journal of Bacteriology, 198 (10), 1487-1498. doi: 10.1128/JB.00791-15
Ben Zakour, Nouri L., Alsheikh-Hussain, Areej S., Ashcroft, Melinda M., Nhu, Nguyen Thi Khanh, Roberts, Leah W., Stanton-Cook, Mitchell, Schembri, Mark A. and Beatson, Scott A. (2016). Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131. MBio, 7 (2) e00347-16, e00347-16.1-e00347-16.11. doi: 10.1128/mBio.00347-16
Moriel, Danilo G., Heras, Begona, Paxman, Jason J., Lo, Alvin W., Tan, Lendl, Sullivan, Matthew J., Dando, Samantha J., Beatson, Scott A., Ulett, Glen C. and Schembri, Mark A. (2016). Molecular and structural characterization of a novel Escherichia coli interleukin receptor mimic protein. mBio, 7 (2) e02046-15, 1-11. doi: 10.1128/mBio.02046-15
Visick, Karen L., Schembri, Mark A., Yildiz, Fitnat and Ghigo, Jean-Marc (2016). Biofilms 2015: multi-disciplinary approaches shed light into microbial life on surfaces. Journal of Bacteriology, 198 (19), 2553-2563. doi: 10.1128/JB.00156-16
Sarkar, Sohinee, Vagenas, Dimitrios, Schembri, Mark A. and Totsika, Makrina (2016). Biofilm formation by multidrug resistant Escherichia coli ST131 is dependent on type 1 fimbriae and assay conditions. Pathogens and Disease, 74 (3) ARTN ftw013, 1-5. doi: 10.1093/femspd/ftw013
You, Lv, Kandale, Ajit, Wun, Shun Jie, McGeary, Ross P., Williams, Simon J., Kobe, Bostjan, Sieber, Volker, Schembri, Mark A., Schenk, Gerhard and Guddat, Luke W. (2016). Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution: A potential target for anti-tuberculosis drug discovery. Febs Journal, 283 (7), 1184-1196. doi: 10.1111/febs.13672
Kapetanovic, Ronan, Bokil, Nilesh J., Achard, Maud E. S., Ong, Cheryl-lynn Y, Peters, Kate M., Stocks, Claudia J., Phan, Minh-Duy, Monteleone, Mercedes, Schroder, Kate, Irvine, Katharine M., Saunders, Bernadette M., Walker, Mark J., Stacey, Katryn J., McEwan, Alastair G., Schembri, Mark A. and Sweet, Matthew J. (2016). Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages. The FASEB Journal, 30 (5), 1901-1912. doi: 10.1096/fj.201500061
Wurpel, Daniel J., Totsika, Makrina, Allsopp, Luke P., Webb, Richard I., Moriel, Danilo G. and Schembri, Mark A. (2016). Comparative proteomics of uropathogenic Escherichia coli during growth in human urine identify UCA-like (UCL) fimbriae as an adherence factor involved in biofilm formation and binding to uroepithelial cells. Journal of Proteomics, 131, 177-189. doi: 10.1016/j.jprot.2015.11.001
Ipe, Deepak S., Ben Zakour, Nouri L., Sullivan, Matthew J., Beatson, Scott A., Ulett, Kimberly B., Benjamin, William H., Davies, Mark R., Dando, Samantha J., King, Nathan P., Cripps, Allan W., Schembri, Mark A., Dougan, Gordon and Ulett, Glen C. (2016). Discovery and Characterization of Human Urine Utilization by Asymptomatic Bacteriuria Streptococcus agalactiae. Infection and Immunity, 84 (1), 307-319. doi: 10.1128/IAI.00938-15
Schaale, K., Peters, K. M., Murthy, A. M., Fritzsche, A. K., Phan, M.-D., Totsika, M., Robertson, A. A. B., Nichols, K. B., Cooper, M. A., Stacey, K. J., Ulett, G. C., Schroder, K., Schembri, M. A. and Sweet, M. J. (2016). Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.. Mucosal Immunology, 9 (1), 124-136. doi: 10.1038/mi.2015.44
Forde, Brian M., Phan, Minh-Duy, Gawthorne, Jayde A., Ashcroft, Melinda M., Stanton-Cook, Mitchell, Sarkar, Sohinee, Peters, Kate M., Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Upton, Mathew, Schembri, Mark A. and Beatson, Scott A. (2015). Lineage-specific methyltransferases define the methylome of the globally disseminated Escherichia coli ST131 clone. MBio, 6 (6) e01602-15, e01602-15. doi: 10.1128/mBio.01602-15
Kakkanat, Asha, Totsika, Makrina, Schaale, Kolja, Duell, Benjamin L., Lo, Alvin W., Phan, Minh-Duy, Moriel, Danilo G., Beatson, Scott A., Sweet, Matthew J., Ulett, Glen C. and Schembri, Mark A. (2015). The role of H4 flagella in Escherichia coli ST131 virulence. Scientific Reports, 5 (16149) 16149, 1-14. doi: 10.1038/srep16149
Zowawi, Hosam M., Forde, Brian M., Alfaresi, Mubarak, Alzarouni, Abdulqadir, Farahat, Yasser, Chong, Teik-Min, Yin, Wai-Fong, Chan, Kok-Gan, Li, Jian, Schembri, Mark A., Beatson, Scott A. and Paterson, David L. (2015). Stepwise evolution of pandrug-resistance in Klebsiella pneumoniae.. Scientific Reports, 5 (Art No.: 15082) 15082, 15082. doi: 10.1038/srep15082
Djoko, Karrera Y., Schembri, Maira M., Donnelly, Paul S., Schembri, Mark A., Shafer, William M. and McEwan, Alastair G. (2015). Copper(II)-bis(thiosemicarbazonato) complexes as antibacterial agents: insights into their mode of action and potential as therapeutics. Antimicrobial Agents and Chemotherapy, 59 (10), 6444-6453. doi: 10.1128/aac.01289-15
Carey, Alison J., Sullivan, Matthew J., Duell, Benjamin L., Crossman, David K., Chattopadhyay, Debasish., Brooks, Andrew J., Tan, Chee K., Crowley, Michael., Sweet, Matthew J., Schembri, Mark A. and Ulett, Glen C. (2015). Uropathogenic Escherichia coli engages CD14-dependent signaling to enable bladder macrophage-dependent control of acute urinary tract infection. The Journal of infectious diseases, 213 (4), 659-668. doi: 10.1093/infdis/jiv424
Zowawi, Hosam M., Harris, Patrick N. A., Roberts, Matthew J., Tambyah, Paul A., Schembri, Mark A., Pezzani, M. Diletta, Williamson, Deborah A. and Paterson, David L. (2015). The emerging threat of multidrug-resistant Gram-negative bacteria in urology. Nature Reviews Urology, 12 (10), 570-584. doi: 10.1038/nrurol.2015.199
Schembri, Mark A., Ben Zakour, Nouri L., Minh-Duy Phan, Forde, Brian M., Stanton-Cook, Mitchell and Beatson, Scott A. (2015). Molecular characterization of the multidrug resistant escherichia coli ST131 clone. Pathogens, 4 (3), 422-430. doi: 10.3390/pathogens4030422
Selkrig, Joel, Belousoff, Matthew J., Headey, Stephen J., Heinz, Eva, Shiota, Takuya, Shen, Hsin-Hui, Beckham, Simone A., Bamert, Rebecca S., Phan, Minh-Duy, Schembri, Mark A., Wilce, Matthew C.J., Scanlon, Martin J., Strugnell, Richard A. and Lithgow, Trevor (2015). Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module.. Scientific Reports, 5 (1) 12905, 12905. doi: 10.1038/srep12905
Wang, Jack T.H., Daly, Joshua N., Willner, Dana L., Patil, Jayee, Hall, Roy A., Schembri, Mark A., Tyson, Gene W. and Hugenholtz, Philip (2015). Do You Kiss Your Mother with That Mouth? An Authentic Large-Scale Undergraduate Research Experience in Mapping the Human Oral Microbiome. Journal of Microbiology and Biology Education, 16 (1), 50-60. doi: 10.1128/jmbe.v16i1.816
Beatson, Scott A., Ben Zakour, Nouri L., Totsika, Makrina, Forde, Brian M., Watts, Rebecca E., Mabbett, Amanda N., Szubert, Jan M., Sarkar, Sohinee, Phan, Minh-Duy, Peters, Kate M., Petty, Nicola K., Alikhan, Nabil-Fareed, Sullivan, Mitchell J., Gawthorne, Jayde A., Stanton-Cook, Mitchell, Nguyen Thi Khanh Nhu, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Hancock, Viktoria, Ussery, David W., Ulett, Glen C. and Schembri, Mark A. (2015). Molecular analysis of asymptomatic bacteriuria Escherichia coli strain VR50 reveals adaptation to the urinary tract by gene acquisition. Infection and Immunity, 83 (5), 1749-1764. doi: 10.1128/IAI.02810-14
Schembri, Mark A., Lo, Alvin W. and Ulett, Glen C. (2015). Blocking the 'MIDAS' touch of Enterococcus faecalis.. Annals of Translational Medicine, 3 (Suppl.1) S3, S3. doi: 10.3978/j.issn.2305-5839.2015.03.32
Phan, Minh Duy, Forde, Brian M., Peters, Kate M., Sarkar, Sohinee, Hancock, Steven, Stanton-Cook, Mitchell, Zakour, Nouri L. Ben, Upton, Mathew, Beatson, Scott A. and Schembri, Mark A. (2015). Molecular Characterization of a Multidrug Resistance IncF Plasmid from the Globally Disseminated Escherichia coli ST131 Clone.. PLoS One, 10 (4) e0122369, e0122369-e0122369. doi: 10.1371/journal.pone.0122369
Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Forde, Brian M., Lo, Alvin W., Stanton-Cook, Mitchell, Roberts, Leah W., Upton, Mathew, Beatson, Scott A. and Schembri, Mark A. (2015). Third-generation cephalosporin resistance conferred by a chromosomally encoded blaCMY-23 gene in the Escherichia coli ST131 reference strain EC958. Journal of Antimicrobial Chemotherapy, 70 (7) dkv066, 1969-1972. doi: 10.1093/jac/dkv066
Wurpel, Daniel J., Moriel, Danilo G., Totsika, Makrina, Easton, Donna M. and Schembri, Mark A. (2015). Comparative analysis of the uropathogenic Escherichia coli surface proteome by tandem mass-spectrometry of artificially induced outer membrane vesicles. Journal of Proteomics, 115, 93-106. doi: 10.1016/j.jprot.2014.12.005
Mavromatis, Charalampos (Harris), Bokil, Nilesh J., Totsika, Makrina, Kakkanat, Asha, Schaale, Kolja, Cannistraci, Carlo V., Ryu, Taewoo, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A., Sweet, Matthew J. and Ravasi, Timothy (2015). The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactions. Cellular Microbiology, 17 (5), 730-746. doi: 10.1111/cmi.12397
Bartley, Paul B., Ben Zakour, Nouri L., Stanton-Cook, Mitchell, Muguli, Raghuram, Prado, Luis, Garnys, Vyt, Taylor, Katherine, Barnett, Timothy C., Pinna, Glen, Robson, Jennifer, Paterson, David L., Walker, Mark J., Schembri, Mark A. and Beatson, Scott A. (2015). Hospital-Wide Eradication of a Nosocomial Legionella pneumophila Serogroup 1 Outbreak. Clinical Infectious Diseases, 62 (3), 273-279. doi: 10.1093/cid/civ870
Carey, Alison J., Tan, Chee K., Ipe, Deepak S., Sullivan, Matthew J., Cripps, Allan W., Schembri, Mark A. and Ulett, Glen C. (2015). Urinary tract infection of mice to model human disease: Practicalities, implications and limitations. Critical Reviews in Microbiology, 42 (5), 780-799. doi: 10.3109/1040841X.2015.1028885
Easton, Donna M., Allsopp, Luke P., Phan, Minh-Duy, Gomes Moriel, Danilo, Goh, Guan Kai, Beatson, Scott A., Mahony, Timothy J., Cobbold, Rowland N. and Schembri, Mark A. (2014). The intimin-like protein FdeC is regulated by H-NS and temperature in Enterohaemorrhagic Escherichia coli. Applied and Environmental Microbiology, 80 (23), 7337-7347. doi: 10.1128/AEM.02114-14
Forde, Brian M., Ben Zakour, Nouri L., Stanton-Cook, Mitchell, Phan, Minh-Duy, Totsika, Makrina, Peters, Kate M., Chan, Kok Gan, Schembri, Mark A., Upton, Mathew and Beatson, Scott A. (2014). The complete genome sequence of Escherichia coli EC958: a high quality reference sequence for the globally disseminated multidrug resistant E. coli O25b:H4-ST131 clone. PLoS One, 9 (8) e104400, e104400.1-e104400.13. doi: 10.1371/journal.pone.0104400
Turni, C., Singh, R., Schembri, M. A. and Blackall, P. J. (2014). Evaluation of a multiplex PCR to identify and serotype Actinobacillus pleuropneumoniae serovars 1, 5, 7, 12 and 15. Letters in Applied Microbiology, 59 (4), 362-369. doi: 10.1111/lam.12287
Kurth, Fabian, Duprez, Wilko, Premkumar, Lakshmanane, Schembri, Mark A., Fairlie, David P. and Martin, Jennifer L. (2014). Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand.. Journal of Biological Chemistry, 289 (28), 19810-19822. doi: 10.1074/jbc.M114.552380
Petty, Nicola K., Ben Zakour, Nouri L., Stanton-Cook, Mitchell, Skippington, Elizabeth, Totsika, Makrina, Forde, Brian M., Phan, Minh-Duy, Gomes Moriel, Danilo, Peters, Kate M., Davies, Mark, Rogers, Benjamin A., Dougan, Gordon, Rodriguez-Baño, Jesús, Pascual, Alvaro, Pitout, Johann D., Upton, Mathew, Paterson, David L., Walsh, Timothy R., Schembri, Mark A. and Beatson, Scott A. (2014). Global dissemination of a multidrug resistant Escherichia coli clone. Proceedings of the National Academy of Sciences, 111 (15), 5694-5699. doi: 10.1073/pnas.1322678111
Sarkar, Sohinee, Ulett, Glen C., Totsika, Makrina, Phan, Minh-Duy and Schembri, Mark A. (2014). Role of capsule and O antigen in the virulence of uropathogenic Escherichia coli. PLoS One, 9 (4) e94786, e94786. doi: 10.1371/journal.pone.0094786
Wurpel, Daniël J., Totsika, Makrina, Allsopp, Luke P., Hartley-Tassell, Lauren E., Day, Christopher J., Peters, Kate M., Sarkar, Sohinee, Ulett, Glen C., Yang, Ji, Tiralongo, Joe, Strugnell, Richard A., Jennings, Michael P. and Schembri, Mark A. (2014). F9 fimbriae of uropathogenic Escherichia coli are expressed at low temperature and recognise Galβ1-3GlcNAc-containing glycans. PLoS One, 9 (3) e93177, e93177. doi: 10.1371/journal.pone.0093177
Willner, Dana, Low, Serene, Steen, Jason A., George, Narelle, Nimmo, Graeme R., Schembri, Mark A. and Hugenholtz, Philip (2014). Single clinical isolates from acute uncomplicated urinary tract infections are representative of dominant In Situ populations. mBio, 5 (2) e01064-13, e01064-13.1-e01064-13.10. doi: 10.1128/mBio.01064-13
Heras, Begona, Totsika, Makrina, Peters, Kate M., Paxman, Jason J., Gee, Christine L., Jarrott, Russell J., Perugini, Matthew A., Whitten, Andrew E. and Schembri, Mark A. (2014). The antigen 43 structure reveals a molecular Velcrolike mechanism of autotransporter-mediated bacterial clumping. Proceedings of the National Academy of Sciences of the United States of America, 111 (1), 457-462. doi: 10.1073/pnas.1311592111
Tan, Christopher J., Bergh, Mary Sarah, Schembri, Mark A. and Johnson, Kenneth A. (2014). Accuracy of Tibial Osteotomy Placement Using 2 Different Tibial Plateau Leveling Osteotomy Jigs. Veterinary Surgery, 43 (5), 525-533. doi: 10.1111/j.1532-950X.2014.12173.x
Pant, Harshita, Hughes, Amy, Schembri, Mark, Miljkovic, Dijana and Krumbiegel, Doreen (2014). CD4+and CD8+ regulatory T cells in chronic rhinosinusitis mucosa. American Journal of Rhinology and Allergy, 28 (2), e83-e89. doi: 10.2500/ajra.2013.28.4014
Premkumar, Lakshmanane, Kurth, Fabian, Neyer, Simon, Schembri, Mark A. and Martin, Jennifer L. (2013). The multidrug resistance IncA/C transferable plasmid encodes a novel domain swapped dimeric protein disulfide isomerase. Journal of Biological Chemistry, Papers in Press (5), 1-24. doi: 10.1074/jbc.M113.516898
Alaidarous, Mohammed Abdullah, Ve, Thomas, Casey, Lachlan, Valkov, Eugene, Ericsson, Daniel, Obayed, Ullah, M., Schembri, Mark A., Mansell, Ashley, Sweet, Matthew J. and Kobe, Bostjan (2013). Mechanism of bacterial interference with TLR4 signaling by Brucella TIR-domain-containing protein TcpB. Journal of Biological Chemistry, 289 (2), 654-668. doi: 10.1074/jbc.M113.523274
Goh, H. M. Sharon, Beatson, Scott A., Totsika, Makrina, Moriel, Danilo G., Phan, Minh-Duy, Szubert, Jan, Runnegar, Naomi, Sidjabat, Hanna E., Paterson, David L., Nimmo, Graeme R., Lipman, Jeffrey and Schembri, Mark A. (2013). Molecular analysis of the Acinetobacter baumannii biofilm-associated protein. Applied and Environmental Microbiology, 79 (21), 6535-6543. doi: 10.1128/AEM.01402-13
Shepherd, Mark, Heras, Begona, Achard, Maud E. S., King, Gordon J., Argente, M. Pilar, Kurth, Fabian, Taylor, Samantha L., Howard, Mark J., King, Nathan P., Schembri, Mark A. and McEwan, Alastair G. (2013). Structural and functional characterization of ScsC, a periplasmic thioredoxin-like protein from Salmonella enterica Serovar typhimurium. Antioxidants and Redox Signaling, 19 (13), 1494-1506. doi: 10.1089/ars.2012.4939
Moriel, Danilo G., Beatson, Scott A., Wurpel, Daniël J., Lipman, Jeffrey, Nimmo, Graeme R., Paterson, David L. and Schembri, Mark A. (2013). Identification of novel vaccine candidates against multidrug-resistant Acinetobacter baumannii. PLoS ONE, 8 (10) e77631, e77631.1-e77631.9. doi: 10.1371/journal.pone.0077631
Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Lukowski, Samuel W., Allsopp, Luke P., Moriel, Danilo Gomes, Achard, Maud E. S., Totsika, Makrina, Marshall, Vikki M., Upton, Mathew, Beatson, Scott A. and Schembri, Mark A. (2013). The serum resistome of a globally disseminated multidrug resistant uropathogenic Escherichia coli clone. PloS Genetics, 9 (10) e1003834, e1003834.1-e1003834.18. doi: 10.1371/journal.pgen.1003834
Alaidarous, Mohammed, Ve, Thomas, Ullah, M. Obayed, Valkov, Eugene, Mansell, Ashley, Schembri, Mark A., Sweet, Matthew J. and Kobe, Bostjan (2013). Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (10), 1167-1170. doi: 10.1107/S1744309113024408
Duell, Benjamin L., Carey, Alison J., Dando, Samantha J., Schembri, Mark A. and Ulett, Glen C. (2013). Human bladder uroepithelial cells synergize with monocytes to promote IL-10 synthesis and other cytokine responses to uropathogenic Escherichia coli. PLoS One, 8 (10) e78013, e78013.1-e78013.14. doi: 10.1371/journal.pone.0078013
Pant, Harshita, Hughes, Amy, Miljkovic, Dijana, Schembri, Mark, Wormald, Peter, Macardle, Peta, Grose, Randall, Zola, Heddy and Krumbiegel, Doreen (2013). Accumulation of effector memory CD8+ T cells in nasal polyps. American Journal of Rhinology and Allergy, 27 (5), e117-e126. doi: 10.2500/ajra.2013.27.3958
Ulett, Kimberly B., Benjamin, William H., Zhuo, Fenglin, Xiao, Meng, Kong, Fanrong, Gilbert, Gwendolyn L., Schembri, Mark A. and Ulett, Glen C. (2013). Diversity of Group B Streptococcus Serotypes Causing Urinary Tract Infection in Adults (vol 47, pg 2055, 2009). Journal of Clinical Microbiology, 51 (8), 2806-2806. doi: 10.1128/JCM.01067-13
Nethercott, Cara, Mabbett, Amanda N., Totsika, Makrina, Peters, Paul, Ortiz, Juan C., Nimmo, Graeme R., Coombs, Geoffrey W., Walker, Mark J. and Schembri, Mark A. (2013). Molecular characterization of endocarditis-associated Staphylococcus aureus. Journal of Clinical Microbiology, 51 (7), 2131-2138. doi: 10.1128/JCM.00651-13
Achard, Maud E. S, Chen, Kaiwen W., Sweet, Matthew J., Watts, Rebecca E., Schroder, Kate, Schembri, Mark A. and McEwan, Alastair G. (2013). An antioxidant role for catecholate siderophores in Salmonella. Biochemical Journal, 454 (3), 543-549. doi: 10.1042/BJ20121771
Stafford, Sian L., Bokil, Nilesh J., Achard, Maud E. S., Kapetanovic, Ronan, Schembri, Mark A., McEwan, Alastair G. and Sweet, Matthew J. (2013). Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper. Bioscience Reports, 33 (4) ARTN e00049, 541-554. doi: 10.1042/BSR20130014
Totsika, Makrina, Kostakioti, Maria, Hannan, Thomas J., Upton, Mathew, Beatson, Scott A., Janetka, James W., Hultgren, Scott J. and Schembri, Mark A. (2013). A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug resistant uropathogenic Escherichia coli ST131. Journal of Infectious Diseases, 208 (6), 921-928. doi: 10.1093/infdis/jit245
Pant, Harshita, Ferguson, Berrylin, Hughes, Amy and Schembri, Mark (2013). Confounding factors in rhinological research. Current Opinion in Otolaryngology and Head and Neck Surgery, 21 (3), 282-292. doi: 10.1097/MOO.0b013e32835fcb07
Ulett, G. C., Makrina Totsika, Kolja Schaale, Carey, A. J., Sweet, Matthew J. and Schembri, Mark A. (2013). Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection. Current Opinion in Microbiology, 16 (1), 100-107. doi: 10.1016/j.mib.2013.01.005
Wurpel, Daniel J., Beatson, Scott A., Totsika, Makrina, Petty, Nicola K. and Schembri, Mark A. (2013). Chaperone-usher fimbriae of Escherichia coli. PLoS One, 85 (1) e52835, e52835.1-e52835.11. doi: 10.1371/journal.pone.0052835
Moriel, Danilo G. and Schembri, Mark A. (2013). Vaccination approaches for the prevention of urinary tract infection. Current Pharmaceutical Biotechnology, 14 (11), 967-974. doi: 10.2174/1389201014666131226144824
Wang, Jack T. H., Schembri, Mark A. and Hall, Roy A. (2013). How much is too much assessment? Insight into assessment-driven student learning gains in large-scale undergraduate microbiology courses. Journal of Microbiology and Biology Education, 14 (1), 12-24. doi: 10.1128/jmbe.v14i1.449
Totsika, Makrina, Moriel, Danilo Gomes, Idris, Adi, Rogers, Benjamin A., Wurpel, Daniel J., Phan, Minh-Duy, Paterson, David L. and Schembri, Mark A. (2012). Uropathogenic Escherichia coli mediated urinary tract infection. Current Drug Targets, 13 (11), 1386-1399. doi: 10.2174/138945012803530206
Watts, Rebecca E., Tan, Chee K., Ulett, Glen C., Carey Alison J., Totsika, Makrina, Idris, Adi, Paton, Adrienne W., Morona, Renato, Paton, James C. and Schembri, Mark A. (2012). Escherichia coli 83972 expressing a P fimbriae oligosaccharide receptor mimic impairs adhesion of uropathogenic E. coli. Journal of Infectious Diseases, 206 (8), 1242-1249. doi: 10.1093/infdis/jis493
Vejborg, Rebecca M., de Evgrafov, Mari R., Phan, Minh Duy, Totsika, Makrina, Schembri, Mark A. and Hancock, Viktoria (2012). Identification of genes important for growth of asymptomatic Bacteriuria Escherichia coli in urine. Infection and Immunity, 80 (9), 3179-3188. doi: 10.1128/IAI.00473-12
Tan, Chee K., Carey, Alison J., Cui, Xiangqin, Webb, Richard I., Ipe, Deepak, Crowley, Michael, Cripps, Allan W., Benjamin, William H. Jr, Ulett, Kimberly B., Schembri, Mark A. and Ulett, Glen C. (2012). Genome-wide mapping of cystitis due to Streptococcus agalactiae and Escherichia coli in mice identifies a unique bladder transcriptome that signifies pathogen-specific antimicrobial defense against urinary tract infection. Infection and Immunity, 80 (9), 3145-3160. doi: 10.1128/IAI.00023-12
Allsopp, Luke P., Beloin, Christophe, Gomes Moriel, Danilo, Totsika, Makrina, Ghigo, Jean-Marc and Schembri, Mark A. (2012). Functional heterogeneity of the UpaH autotransporter protein from uropathogenic Escherichia coli. Journal of Bacteriology, 194 (21), 5769-5782. doi: 10.1128/JB.01264-12
Thompson, Mary F., Schembri, Mark A., Mills, Paul C. and Trott, Darren J. (2012). A modified three-dose protocol for colonization of the canine urinary tract with the asymptomatic bacteriuria Escherichia coli strain 83972. Veterinary Microbiology, 158 (3-4), 446-450. doi: 10.1016/j.vetmic.2012.03.012
Achard, Maud E. S., Stafford, Sian L., Bokil, Nilesh J., Chartres, Jy, Bernhardt, Paul V., Schembri, Mark A., Sweet, Matthew J. and McEwan, Alastair G. (2012). Copper redistribution in murine macrophages in response to Salmonella infection. Biochemical Journal, 444 (1), 51-57. doi: 10.1042/BJ20112180
Selkrig, Joel, Mosbahi, Khedidja, Webb, Chaille T., Belousoff, Matthew J., Perry, Andrew J., Wells, Timothy J., Morris, Faye, Leyton, Denisse L., Totsika, Makrina, Phan, Minh-Duy, Celik, Nermin, Kelly, Michelle, Oates, Clare, Hartland, Elizabeth L., Robins-Browne, Roy M., Ramarathinam, Sri Harsha, Purcell, Anthony W., Schembri, Mark A., Strugnell, Richard A., Henderson, Ian R., Walker, Daniel and Lithgow, Trevor (2012). Discovery of an archetypal protein transport system in bacterial outer membranes. Nature Structural and Molecular Biology, 19 (5), 506-510. doi: 10.1038/nsmb.2261
Hannan, Thomas J., Totsika, Makrina, Mansfield, Kylie J., Moore, Kate H., Schembri, Mark A. and Hultgren, Scott J. (2012). Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiology Reviews, 36 (3), 616-648. doi: 10.1111/j.1574-6976.2012.00339.x
Totsika, Makrina, Wells, Timothy J., Beloin, Christophe, Valle, Jaione, Allsopp, Luke P., King, Nathan P., Ghigo, Jean-Marc and Schembri, Mark A. (2012). Molecular characterization of the EhaG and UpaG trimeric autotransporter proteins from pathogenic Escherichia coli. Applied and Environmental Microbiology, 78 (7), 2179-2189. doi: 10.1128/AEM.06680-11
King, Nathan P, Sakinc, Turkan, Ben Zakour, Nouri L, Totsika, Makrina, Heras, Begona, Simerska, Pavla, Shepherd, Mark, Gatermann, Soren G, Beatson, Scott A and Schembri, Mark A (2012). Characterisation of a cell wall-anchored protein of Staphylococcus saprophyticus associated with linoleic acid resistance. BMC Microbiology, 12 (1) 8, 8.1-8.25. doi: 10.1186/1471-2180-12-8
Duell, Benjamin L., Carey, Alison J., Tan, Chee K., Cui, Xiangqin, Webb, Richard I., Totsika, Makrina, Schembri, Mark A., Derrington, Petra, Irving-Rodgers, Helen, Brooks, Andrew J., Cripps, Allan W., Crowley, Michael and Ulett, Glen C. (2012). Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense against bacterial urinary tract infection. Journal of Immunology, 188 (2), 781-792. doi: 10.4049/jimmunol.1101231
Watts, Rebecca E., Totsika, Makrina, Challinor, Victoria L., Mabbett, Amanda N., Ulett, Glen C., De Voss, James J. and Schembri, Mark A. (2012). Contribution of siderophore systems to growth and urinary tract colonization of asymptomatic bacteriuria Escherichia coli. Infection and Immunity, 80 (1-2), 333-344. doi: 10.1128/IAI.05594-11
Allsopp, Luke P., Beloin, Christophe, Ulett, Glen C., Valle, Jaione, Totsika, Makrina, Sherlock, Orla, Ghigo, Jean-Marc and Schembri, Mark A. (2012). Molecular characterization of UpaB and UpaC, two new autotransporter proteins of uropathogenic Escherichia coli CFT073. Infection and Immunity, 80 (1), 321-332. doi: 10.1128/IAI.05322-11
Wang, Jack T.H., Schembri, Mark A., Ramakrishna, Mathitha, Sagulenko, Evgeny and Fuerst, John A. (2012). Immersing undergraduate students in the research experience: A practical laboratory module on molecular cloning of microbial genes. Biochemistry and Molecular Biology Education, 40 (1), 37-45. doi: 10.1002/bmb.20572
Abraham, Sam, Chapman, Toni A., Zhang, Ren, Chin, James, Mabbett, Amanda N., Totsika, Makrina and Schembri Mark A. (2011). Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections. Journal of Clinical Microbiology, 50 (3), 1027-1030. doi: 10.1128/JCM.06671-11
Bokil, Nilesh J., Totsika, Makrina, Carey, Alison J., Stacey, Katryn J., Hancock, Viktoria, Saunders, Bernadette M., Ravasi, Timothy, Ulett, Glenn C., Schembri, Mark A. and Sweet, Matthew J. (2011). Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages. Immunobiology, 216 (11), 1164-1171. doi: 10.1016/j.imbio.2011.05.011
Totsika, Makrina, Beatson, Scott A., Sarkar, Sohinee, Phan, Minh-Duy, Petty, Nicola K., Bachmann, Nathan, Szubert, Marek, Sidjabat, Hanna E., Paterson, David L., Upton, Mathew and Schembri, Mark A. (2011). Insights into a multidrug resistant escherichia coli pathogen of the globally disseminated ST131 lineage: Genome analysis and virulence mechanisms. Plos One, 6 (10) e26578, e26578-1-e26578-11. doi: 10.1371/journal.pone.0026578
Wilksch, Jonathan J., Yang, Ji, Clements, Abigail, Gabbe, Jacinta L., Short, Kirsty R., Cao, Hanwei, Cavaliere, Rosalia, James, Catherine E., Whitchurch, Cynthia B., Schembri, Mark A., Chuah, Mary L. C., Liang, Zhao-Xun, Wijburg, Odilia L., Jenney, Adam W., Lithgow, Trevor and Strugnell, Richard A. (2011). MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression. PloS Pathogens, 7 (8) e1002204, e1002204. doi: 10.1371/journal.ppat.1002204
Rossiter, Amanda E., Leyton, Denisse L., Tveen-Jensen, Karina, Browning, Douglas F., Sevastsyanovich, Yanina, Knowles, Timothy J., Nichols, Katie B., Cunningham, Adam F., Overduin, Michael, Schembri, Mark A. and Henderson, Ian R. (2011). The essential beta-barrel assembly machinery complex components BamD and BamA are required for autotransporter biogenesis. Journal of Bacteriology, 193 (16), 4250-4253. doi: 10.1128/JB.00192-11
Easton, Donna M., Totsika, Makrina, Allsopp, Luke P., Phan, Minh-Duy, Idris, Adi, Wurpel, Daniël J., Sherlock, Orla, Zhang, Bing, Venturini, Carola, Beatson, Scott A., Mahony, Timothy J., Cobbold, Rowland N. and Schembri, Mark A. (2011). Characterization of EhaJ, a new autotransporter protein from enterohemorrhagic and enteropathogenic Escherichia coli. Frontiers in Microbiology: Frontiers in Cellular and Infection Microbiology, 2 (JUNE), 120.1-120.9. doi: 10.3389/fmicb.2011.00120
Vejborg, Rebecca Munk, Hancock, Viktoria, Schembri, Mark A. and Klemm, Per (2011). Comparative Genomics of Escherichia coli Strains Causing Urinary Tract Infections. Applied and Environmental Microbiology, 77 (10), 3268-3278. doi: 10.1128/AEM.02970-10
Shouldice, Stephen R., Heras, Begona, Walden, Patricia M., Totsika, Makrina, Schembri, Mark A. and Martin, Jennifer L. (2011). Structure and function of DsbA, a key bacterial oxidative folding catalyst. Antioxidants and Redox Signaling, 14 (9), 1729-1760. doi: 10.1089/ars.2010.3344
King, Nathan P., Beatson, Scott A., Totsika, Makrina, Ulett, Glen C., Alm, Richard A., Manning, Paul A. and Schembri, Mark A. (2011). UafB is a serine-rich repeat adhesin of Staphylococcus saprophyticus that mediates binding to fibronectin, fibrinogen and human uroepithelial cells. Microbiology, 157 (4), 1161-1175. doi: 10.1099/mic.0.047639-0
Pope, Phillip B., Totsika, Makrina, de Carcer, Daniel Aguirre, Schembri, Mark A. and Morrison, Mark (2011). Muramidases found in the foregut microbiome of the Tammar wallaby can direct cell aggregation and biofilm formation. ISME Journal, 5 (2), 341-350. doi: 10.1038/ismej.2010.116
Duell, Benjamin, Cripps, Allan W., Schembri, Mark A. and Ulett, Glen C. (2011). Epithelial cell coculture models for studying infectious diseases: Benefits and limitations. Journal of Biomedicine and Biotechnology, 2011 (1) 852419, 1-9. doi: 10.1155/2011/852419
Thompson, Mary F., Totsika, Makrina, Schembri, Mark A., Mills, Paul C., Seton, Erica J. and Trott, Darren J. (2011). Experimental colonization of the canine urinary tract with the asymptomatic bacteriuria Escherichia coli strain 83972. Veterinary Microbiology, 147 (1-2), 205-208. doi: 10.1016/j.vetmic.2010.06.007
Runnegar, N., Sidjabat, H., Goh, H. M. S., Nimmo, G. R., Schembri, M. A. and Paterson, D. L. (2010). Molecular epidemiology of multidrug-resistant Acinetobacter baumannii in a single institution over a 10-year period. Journal of Clinical Microbiology, 48 (11), 4051-4056. doi: 10.1128/JCM.01208-10
Klemm, Per, Hancock, Viktoria and Schembri, Mark A. (2010). Fimbrial adhesins from extraintestinal Escherichia coli. Environmental Microbiology Reports, 2 (5), 628-640. doi: 10.1111/j.1758-2229.2010.00166.x
Wells, Timothy J., Totsika, Makrina and Schembri, Mark A. (2010). Autotransporters of Escherichia coli: A sequence-based characterization. Microbiology, 156 (8), 2459-2469. doi: 10.1099/mic.0.039024-0
Watts, Rebecca E., Hancock, Viktoria, Ong, Cheryl-Lynn Y., Vejborg, Rebecca Munk, Mabbett, Amanda N., Totsika, Makrina, Looke, David F., Nimmo, Graeme R., Klemm, Per and Schembri, Mark A. (2010). Escherichia coli isolates causing asymptomatic bacteriuria in catheterized and noncatheterized individuals possess similar virulence properties. Journal of Clinical Microbiology, 48 (7), 2449-2458. doi: 10.1128/JCM.01611-09
Ong, Cheryl-lynn Y., Beatson, Scott A., Totsika, Makrina, Forestier, Christiane, McEwan, Alastair G. and Schembri, Mark A. (2010). Molecular analysis of type 3 fimbrial genes from Escherichia coli, Klebsiella and Citrobacter species. BMC Microbiology, 10 (183) 183, 1-12. doi: 10.1186/1471-2180-10-183
Heras, B, Totsika, M, Jarrott, R, Shouldice, SR, Guncar, G, Achard, MES, Wells, TJ, Argente, MP, McEwan, AG and Schembri, MA (2010). Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium. Journal of Biological Chemistry, 285 (24), 18423-18432. doi: 10.1074/jbc.M110.101360
Achard, Maud E. S., Tree, Jai J., Holden, James A., Simpfendorfer, Kim R., Wijburg, Odilia L. C., Strugnell, Richard A., Schembri, Mark A., Sweet, Matthew J., Jennings, Michael P. and McEwan, Alastair G. (2010). The multi-copper-ion oxidase CueO of Salmonella enterica serovar Typhimurium is required for systemic virulence. Infection and Immunity, 78 (5), 2312-2319. doi: 10.1128/IAI.01208-09
Jarrott, R., Shouldice, S.R., Guncar, G., Totsika, M., Schembri, M.A. and Heras, B. (2010). Expression and crystallization of SeDsbA, SeDsbL and SeSrgA from Salmonella enterica serovar Typhimurium. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 66 (Part 5), 601-604. doi: 10.1107/S1744309110011942
Vejborg, Rebecca Munk, Friis, Carsten, Hancock, Viktoria, Schembri, Mark A. and Klemm, Per (2010). A virulent parent with probiotic progeny: Comparative genomics of Escherichia coli strains CFT073, Nissle 1917 and ABU 83972. Molecular Genetics and Genomics, 283 (5), 469-484. doi: 10.1007/s00438-010-0532-9
Doidge, Michelle, Allworth, Anthony M., Woods, Marion, Marshall, Penelope, Terry, Marshall, O'Brien, Kathryn, Goh, Hwee Mian, George, Narelle, Nimmo, Graeme R., Schembri, Mark A., Lipman, Jeffery and Paterson, David L. (2010). Control of an outbreak of carbapenem-resistant Acinetobacter baumannii in Australia after introduction of environmental cleaning with a commercial oxidizing disinfectant. Infection Control and Hospital Epidemiology, 31 (4), 418-420. doi: 10.1086/651312
Allsopp, Luke P., Totsika, Makrina, Tree, Jai J., Ulett, Glen C., Mabbett, Amanda N., Wells, Timothy J., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2010). UpaH is a newly identified autotransporter protein that contributes to biofilm formation and bladder colonization by uropathogenic Escherichia coli CFT073. Infection and Immunity, 78 (4), 1659-1669. doi: 10.1128/IAI.01010-09
Ulett, Glen C., Webb, Richard I., Ulett, Kimberly B., Cui, Xiangqin, Benjamin, William H., Crowley, Michael and Schembri, Mark A. (2010). Group B Streptococcus (GBS) urinary tract infection involves binding of GBS to bladder uroepithelium and potent but GBS-specific induction of interleukin 1 alpha. The Journal of Infectious Diseases, 201 (6), 866-870. doi: 10.1086/650696
Achard, Maud E. S., Hamilton, Amanda J., Dankowski, Tarek, Heras, Begona, Schembri, Mark A., Edwards, Jennifer L., Jennings, Michael P. and McEwan, Alastair G. (2009). A periplasmic thioredoxin-like protein plays a role in defense against oxidative stress in Neisseria gonorrhoeae. Infection And Immunity, 77 (11), 4934-4939. doi: 10.1128/IAI.00714-09
Ong, Cheryl-Lynn Y., Beatson, Scott A., McEwan, Alastair G. and Schembri, Mark A. (2009). Conjugative plasmid transfer and adhesion dynamics in an Escherichia coli Biofilm. Applied and Environmental Microbiology, 75 (21), 6783-6791. doi: 10.1128/AEM.00974-09
Pant, Harshita, Schembri, Mark A., Wormald, Peter J. and Macardle, Peter J. (2009). IgE-mediated fungal allergy in allergic fungal sinusitis. Laryngoscope, 119 (6), 1046-1052. doi: 10.1002/lary.20170
Ulett, Kimberly B., Benjamin, William H., Zhuo, Fenglin, Xiao, Meng, Kong, Fanrong, Gilbert, Gwendolyn L., Schembri, Mark A. and Ulett, Glen C. (2009). Diversity of Group B Streptococcus serotypes causing urinary tract infection in adults. Journal of Clinical Microbiology, 47 (7), 2055-2060. doi: 10.1128/JCM.00154-09
Totsika, Makrina, Heras, Begona, Wurpel, Daniel J. and Schembri, Mark A. (2009). Characterization of two homologous disulfide bond systems involved in virulence factor biogenesis in uropathogenic Escherichia coli CFT073. Journal of Bacteriology, 191 (12), 3901-3908. doi: 10.1128/JB.00143-09
Wells, Timothy J., McNeilly, Tom N., Totsika, Makrina, Mahajan, Arvind, Gally, David L. and Schembri, Mark A. (2009). The Escherichia coli O157:H7 EhaB autotransporter protein binds to laminin and collagen I and induces a serum IgA response in O157:H7 challenged cattle. Environmental Microbiology, 11 (7), 1803-1814. doi: 10.1111/j.1462-2920.2009.01905.x
Heras, B, Shouldice, S. R., Totsika, M, Scanlon, M. J., Schembri, M. A. and Martin, J. L. (2009). DSB proteins and bacterial pathogenicity. Nature Reviews Microbiology, 7 (3), 215-225. doi: 10.1038/nrmicro2087
Mabbett, Amanda N., Ulett, Glen C., Watts, Rebecca E., Tree, Jai J., Totsika, Makrina, Ong, Cheryl-Lynn, Wood, Jacqueline M., Monaghan, Wayne, Looke, David F., Nimmo, Graeme R., Svanborg, Catharina and Schembri, Mark A. (2009). Virulence properties of asymptomatic bacteriuria Escherichia coli. International Journal of Medical Microbiology, 299 (1), 53-63. doi: 10.1016/j.ijmm.2008.06.003
Sidjabat, Hanna E., Chin, James J.-C., Chapman, Toni, Wu, Kent, Ulett, Glen C., Cheryl-Lynn Ong, Schembri, Mark A., Johnson, James R. and Trott, Darren J. (2009). Colonisation dynamics and virulence of two clonal groups of multidrug-resistant Escherichia coli isolated from dogs. Microbes and Infection, 11 (1), 100-107. doi: 10.1016/j.micinf.2008.10.014
Tree, Jai J., Ulett, Glen C., Ong, Cheryl-Lynn Y., Trott, Darren J., McEwan, Alastair G. and Schembri, Mark A. (2008). Trade-off between iron uptake and protection against oxidative stress: Deletion of cueO promotes uropathogenic Escherichia coli virulence in a mouse model of urinary tract infection. Journal of Bacteriology, 190 (20), 6909-6912. doi: 10.1128/JB.00451-08
Valle, Jaione, Mabbett, Amanda N., Ulett, Glen C., Toledo-Arana, Alejandro, Wecker, Karine, Totsika. Makrina, Schembri, Mark A., Ghigo, Jean-Marc and Beloin, Christophe (2008). UpaG, a new member of the trimeric autotransporter family of adhesins in uropathogenic Escherichia coli. Journal of Bacteriology, 190 (12), 4147-4161. doi: 10.1128/JB.00122-08
Ong, C., Ulett, G., Mabbett, A., Beatson, S., Webb, R., Monaghan, W., Nimmo, G., Looke, D., McEwan, A. and Schembri, M. (2008). Identification of Type 3 Fimbriae in Uropathogenic Escherichia coli Reveals a Role in Biofilm Formation. Journal of Bacteriology, 190 (3), 1054-1063. doi: 10.1128/JB.01523-07
Wells, T.J., Sherlock, O., Rivas, L., Mahajan, A., Beatson, S.A., Torpdahl, M., Webb, R.I., Allsopp, L., Gobius, K., Gally, D.L. and Schembri, M.A. (2008). EhaA is a novel autotransporter protein of enterohemorrhagic Escherichia coli O157:H7 that contributes to adhesion and biofilm formation. Environmental Microbiology, 10 (3), 589-604. doi: 10.1111/j.1462-2920.2007.01479.x
Klemm, P., Hancock, V., Kvist, M. and Schembri, M. (2007). Candidate targets for new antivirulence drugs: selected cases of bacterial adhesion and biofilm formation. Future Microbiology, 2 (6), 643-653. doi: 10.2217/17460913.2.6.643
Wells, T. J., Tree, J. J., Ulett, G. C. and Schembri, M. A. (2007). Autotransporter proteins: novel targets at the bacterial cell surface. Fems Microbiology Letters, 274 (2), 163-172. doi: 10.1111/j.1574-6968.2007.00833.x
Nilsson, LM, Yakovenko, O, Tchesnokova, V, Thomas, WE, Schembri, MA, Vogel, V, Klemm, P and Sokurenko, EV (2007). The cysteine bond in the Escherichia coli FimH adhesin is critical for adhesion under flow conditions. Molecular Microbiology, 65 (5), 1158-1169. doi: 10.1111/j.1365-2958.2007.05858.x
Klemm, Per, Hancock, Viktoria and Schembri, Mark A. (2007). Mellowing out: Adaptation to commensalism by Escherichia coli asymptomatic bacteriuria strain 83972. Infection and Immunity, 75 (8), 3688-3695. doi: 10.1128/IAI.01730-06
Ulett, Glen C., Valle, Jaione, Beloin, Christophe, Sherlock, Orla, Ghigo, Jean-Marc and Schembri, Mark A. (2007). Functional analysis of antigen 43 in uropathogenic Escherichia coli reveals a role in long-term persistence in the urinary tract. Infection and Immunity, 75 (7), 3233-3244. doi: 10.1128/IAI.01952-06
Tree, JJ, Ulett, GC, Hobman, JL, Constantinidou, C, Brown, NL, Kershaw, C, Schembri, MA, Jennings, MP and McEwan, AG (2007). The multicopper oxidase (CueO) and cell aggregation in Escherichia coli. Environmental Microbiology, 9 (8), 2110-2116. doi: 10.1111/j.1462-2920.2007.01320.x
Bergsten, G, Wullt, B, Schembri, MA, Leijonhufvud, I and Svanborg, C (2007). Do type 1 fimbriae promote inflammation in the human urinary tract?. Cellular Microbiology, 9 (7), 1766-1781. doi: 10.1111/j.1462-5822.2007.00912.x
Ulett, GC, Mabbett, AN, Fung, KC, Webb, RI and Schembri, MA (2007). The role of F9 fimbriae of uropathogenic Escherichia coli in biofilm formation. Microbiology-sgm, 153 (7), 2321-2331. doi: 10.1099/mic.0.2006/004648-0
Ulett, G. C., Webb, R. I. and Schembri, M. A. (2006). Antigen-43-mediated autoaggregation impairs motility in Escherichia coli. Microbiology-sgm, 152 (9), 2101-2110. doi: 10.1099/mic.0.28607-0
Bouckaert, J., Berglund, J., Schembri, M., De Genst, E., Cools, L., Wuhrer, M., Hung, C. S., Pinkner, J., Slattegard, R., Zavialov, A., Choudhury, D., Langermann, S., Hultgren, S. J., Wyns, L., Klemm, P., Oscarson, S., Knight, S. D. and De Greve, H. (2006). Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin. Journal of Urology, 175 (4), 1570-1570. doi: 10.1016/S0022-5347(05)00871-2
Roos, Viktoria, Ulett, Glen C., Schembri, Mark A. and Klemm, Per (2006). The asymptomatic bacteriuria Escherichia coli strain 83972 outcompetes uropathogenic E-coli strains in human urine. Infection and Immunity, 74 (1), 615-624. doi: 10.1128/IAI.74.1.615-624.2006
Klemm, Per, Roos, Victoria, Ulett, Glen C., Svanborg, Catharina and Schembri, Mark A. (2006). Molecular characterization of the Escherichia coli asymptomatic bacteriuria strain 83972: The taming of a pathogen. Infection and Immunity, 74 (1), 781-785. doi: 10.1128/IAI.74.1.781-785.2006
Muniesa, Maite, Schembri, Mark A., Hauf, Nadja and Chakraborty, Trinad (2006). Active genetic elements present in the locus of enterocyte effacement in Escherichia coli O26 and their role in mobility. Infection and Immunity, 74 (7), 4190-4199. doi: 10.1128/IAI.00926-05
Roos, Viktoria, Schembri, Mark A., Ulett, Glen C. and Klemm, Per (2006). Asymptomatic bacteriuria Escherichia coli strain 83972 carries mutations in the foc locus and is unable to express F1C fimbriae. Microbiology, 152 (Part 6), 1799-1806. doi: 10.1099/mic.0.28711-0
Schembri, Mark A., Blom, Jens, Krogfelt, Karen A. and Klemm, Per (2005). Capsule and fimbria interaction in Klebsiella pneumoniae. Infection and Immunity, 73 (8), 4626-4633. doi: 10.1128/IAI.73.8.4626-4633.2005
Bouckaert, Julie, Berglund, Jenny, Schembri, Mark, De Genst, Erwin, Cool, Lieve, Wuhrer, Manfred, Hung, Chia-Suei, Pinkner, Jerome, Slattegard, Rikard, Zavialov, Anton, Choudhury, Devapriya, Langermann, Solomon, Hultgren, Scott J., Wyns, Lode and Klemm, Per (2005). Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin. Molecular Microbiology, 55 (2), 441-455. doi: 10.1111/j.1365-2958.2004.04415.x
Sherlock, Orla, Schembri, Mark A., Reisner, Andreas and Klemm, Per (2004). Novel roles for the AIDA adhesion from diarrheagenic Escherichia coli: Cell aggregation and biofilm formation. Journal of Bacteriology, 186 (23), 8058-8065. doi: 10.1128/JB.186.23.8058-8065.2004
Schembri, Mark A., Dalsgaard, Dorte and Klemm, Per (2004). Capsule shields the function of short bacterial adhesins. Journal of Bacteriology, 186 (5), 1249-1257. doi: 10.1128/JB.186.5.1249-1257.2004
Hansen, E. H., Schembri, M. A., Klemm, P., Schafer, T., Molin, S. and Gram, L. (2004). Elucidation of the antibacterial mechanism of the Curvularia haloperoxidase system by DNA microarray profiling. Applied And Environmental Microbiology, 70 (3), 1749-1757. doi: 10.1128/AEM.70.3.1749-1757.2004
Klemm, P., Hjerrild, L., Gjermansen, M. and Schembri, M. A. (2004). Structure-function analysis of the self-recognizing Antigen 43 autotransporter protein from Escherichia coli. Molecular Microbiology, 51 (1), 283-296. doi: 10.1046/j.1365-2958.2003.03833.x
Klemm, Per and Schembri, Mark (2004). Type 1 fimbriae, curli, and antigen 43: Adhesion, colonization, and biofilm formation. EcoSal Plus, 1 (1) ecosalplus.8.3.2.6. doi: 10.1128/ecosalplus.8.3.2.6
Hentzer, Morten, Wu, Hong, Andersen, Jens Bo, Riedel, Kathrin, Rasmussen, Thomas B., Bagge, Niels, Kumar, Naresh, Schembri, Mark A., Song, Zhijun, Kristoffersen, Peter, Manefield, Mike, Costerton, John W., Molin, Søren, Eberl, Leo and Steinberg, Peter (2003). Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. Embo Journal, 22 (15), 3803-3815. doi: 10.1093/emboj/cdg366
Reisner, A., Haagensen, J. A. J., Schembri, M. A., Zechner, E. L. and Molin, S. (2003). Development and maturation of Escherichia coli K-12 biofilms. Molecular Microbiology, 48 (4), 933-946. doi: 10.1046/j.1365-2958.2003.03490.x
Schembri, Mark A., Hjerrild, Louise, Gjermansen, Morten and Klemm, Per (2003). Differential expression of the Escherichia coli autoaggregation factor antigen 43. Journal of Bacteriology, 185 (7), 2236-2242. doi: 10.1128/JB.185.7.2236-2242.2003
Schembri, M. A., Kjaergaard, K. and Klemm, P. (2003). Global gene expression in Escherichia coli biofilms. Molecular Microbiology, 48 (1), 253-267. doi: 10.1046/j.1365-2958.2003.03432.x
Kjaergaard, K., Hasman, H., Schembri, M. A. and Klemm, P. (2002). Antigen 43-mediated autotransporter display, a versatile bacterial cell surface presentation system. Journal of Bacteriology, 184 (15), 4197-4204. doi: 10.1128/JB.184.15.4197-4204.2002
Schembri, M. A., Ussery, D. W., Workman, C., Hasman, H. and Klemm, P. (2002). DNA microarray analysis of fim mutations in Escherichia coli. Molecular Genetics And Genomics, 267 (6), 721-729. doi: 10.1007/s00438-002-0705-2
Schembri, Mark A., Givskov, Michael and Klemm, Ker (2002). An Attractive Surface: Gram-Negative Bacterial Biofilms. Signal Transduction Knowledge Environment, 132 (132), RE6-re6. doi: 10.1126/stke.2002.132.re6
Schembri, Mark A, Givskov, Michael and Klemm, Per (2002). An attractive surface: gram-negative bacterial biofilms. Science's STKE : signal transduction knowledge environment, 2002 (132)
Schembri, M. A., Neilan, B. A. and Saint, C. P. (2001). Identification of genes implicated in toxin production in the cyanobacterium Cylindrospermopsis raciborskii. Environmental Toxicology, 16 (5), 413-421. doi: 10.1002/tox.1051
Schembri, M. A., Christiansen, G. and Klemm, P. (2001). FimH-mediated autoaggregation of Escherichia coli. Molecular Microbiology, 41 (6), 1419-1430. doi: 10.1046/j.1365-2958.2001.02613.x
Sokurenko, E. V., Schembri, M. A., Trintchina, E., Kjaergaard, K., Hasty, D. L. and Klemm, P. (2001). Valency conversion in the type 1 fimbrial adhesin of Escherichia coli. Molecular Microbiology, 41 (3), 675-686. doi: 10.1046/j.1365-2958.2001.02545.x
Schembri, M. A. and Klemm, P. (2001). Coordinate gene regulation by fimbriae-induced signal transduction. EMBO Journal, 20 (12), 3074-3081. doi: 10.1093/emboj/20.12.3074
Schembri, Mark A. and Klemm, Per (2001). Biofilm formation in a hydrodynamic environment by novel FimH variants and ramifications for virulence. Infection and Immunity, 69 (3), 1322-1328. doi: 10.1128/IAI.69.3.1322-1328.2001
Schembri, M. A., Kjaergaard, K., Sokurenko, E. V. and Klemm, P. (2001). Molecular characterization of the Escherichia coli FimH adhesin. Journal of Infectious Diseases, 183 (Suppl 1), S28-S31. doi: 10.1086/318847
Kjaergaard, K., Schembri, M. A. and Klemm, P. (2001). Novel Zn2+-chelating peptides selected from a fimbria-displayed random peptide library. Applied And Environmental Microbiology, 67 (12), 5467-5473. doi: 10.1128/AEM.67.12.5467-5473.2001
Klemm, Per and Schembri, Mark A. (2000). Fimbrial surface display systems in bacteria: from vaccines to random libraries. Microbiology, 146 (12), 3025-3032. doi: 10.1099/00221287-146-12-3025
Kjærgaard, Kristian, Schembri, Mark A., Ramos, Cayo, Molin, Søren and Klemm, Per (2000). Antigen 43 facilitates formation of multispecies biofilms. Environmental Microbiology, 2 (6), 695-702. doi: 10.1046/j.1462-2920.2000.00152.x
Kjaergaard, Kristian, Schembri, Mark A., Hasman, Henrik and Klemm, Per (2000). Antigen 43 from Escherichia coli induces inter- and intraspecies cell aggregation and changes in colony morphology of Pseudomonas fluorescens. Journal of Bacteriology, 182 (17), 4789-4796. doi: 10.1128/JB.182.17.4789-4796.2000
Schembri, Mark A., Hasman, Henrik and Klemm, Per (2000). Expression and purification of the mannose recognition domain of the FimH adhesin. FEMS Microbiology Letters, 188 (2), 147-151. doi: 10.1016/S0378-1097(00)00228-7
Klemm, P. and Schembri, M.A. (2000). Fimbriae-assisted bacterial surface display of heterologous peptides. International Journal of Medical Microbiology, 290 (3), 215-221.
Schembri, Mark A., Sokurenko, Evgeni V. and Klemm, Per (2000). Functional flexibility of the FimH adhesin: Insights from a random mutant library. Infection and Immunity, 68 (5), 2638-2646. doi: 10.1128/IAI.68.5.2638-2646.2000
Klemm, Per and Schembri, Mark A. (2000). Bacterial adhesins: Function and structure. International Journal of Medical Microbiology, 290 (1), 27-35.
Hasman, Henrik, Schembri, Mark A. and Klemm, Per (2000). Antigen 43 and type 1 fimbriae determine colony morphology of Escherichia coli K-12. Journal of Bacteriology, 182 (4), 1089-1095. doi: 10.1128/JB.182.4.1089-1095.2000
Wilson, KM, Schembri, MA, Baker, PD and Saint, CP (2000). Molecular characterization of the toxic cyanobacterium Cylindrospermopsis raciborskii and design of a species-specific PCR. Applied And Environmental Microbiology, 66 (1), 332-338. doi: 10.1128/AEM.66.1.332-338.2000
Kjaergaard, Kristian, Sorensen, Jack K., Schembri, Mark A. and Klemm, Per (2000). Sequestration of zinc oxide by fimbrial designer chelators. Applied and Environmental Microbiology, 66 (1), 10-14. doi: 10.1128/AEM.66.1.10-14.2000
Sokurenko, E. V., Chesnokova, V., Dykhuizen, D. E., Ofek, I., Wu, X. R., Krogfelt, K. A., Struve, C., Schembri, M. A., Hasty, D. L. and Cowan, M. M. (1999). Pathogenic adaptation of Escherichia coli by natural variation of the fimH adhesin. Chemtracts, 12 (13), 944-948.
Schembri, Mark A., Kjaergaard, Kristian and Klemm, Per (1999). Bioaccumulation of heavy metals by fimbrial designer adhesins. FEMS Microbiology Letters, 170 (2), 363-371. doi: 10.1111/j.1574-6968.1999.tb13396.x
Schembri, M. A., Olsen, P. B. and Klemm, P. (1998). Orientation-dependent enhancement by H-NS of the activity of the type 1 fimbrial phase switch promoter in Escherichia coli. Molecular and General Genetics, 259 (3), 336-344. doi: 10.1007/s004380050820
Sokurenko, Evgeni V., Chesnokova, Veronika, Dykhuizen, Daniel E., Ofek, Itzhak, Wu, Xue-Ru, Krogfelt, Karen A., Struve, Carsten, Schembri, Mark A. and Hasty, David L. (1998). Pathogenic adaptation of Escherichia coli by natural variation of the FimH adhesin. Proceedings of the National Academy of Sciences of the United States of America, 95 (15), 8922-8926. doi: 10.1073/pnas.95.15.8922
Schembri, Mark A. and Klemm, Per (1998). Heterobinary adhesins based on the Escherichia coli FimH fimbrial protein. Applied and Environmental Microbiology, 64 (5), 1628-1633.
Olsen, Peter B., Schembri, Mark A., Gally, David L. and Klemm, Per (1998). Differential temperature modulation by H-NS of the fimB and fimE recombinase genes which control the orientation of the type 1 fimbrial phase switch. FEMS Microbiology Letters, 162 (1), 17-23. doi: 10.1111/j.1574-6968.1998.tb12973.x
Lin, SK, Lambert, JR, Schembri, MA, Nicholson, L and Johnson, IH (1998). The prevalence of Helicobacter pylori in practising dental staff and dental students. Australian Dental Journal, 43 (1), 35-39. doi: 10.1111/j.1834-7819.1998.tb00150.x
Klemm, Per, Schembri, Mark, Stentebjerg-Olesen, Bodhil, Hasman, Henrik and Hasty, David L. (1998). 6.6 Fimbriae: Detection, purification, and characterization. Methods in Microbiology, 27 (C), 239-248. doi: 10.1016/S0580-9517(08)70287-3
Moore, Robert J., Vernon-Roberts, Barrie, Fraser, Robert D., Osti, Orso L. and Schembri, Mark (1996). The origin and fate of herniated lumbar intervertebral disc tissue. Spine, 21 (18), 2149-2155. doi: 10.1097/00007632-199609150-00018
Connell, H., Agace, W., Schembri, M. and Marild, S. (1996). Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract. Proceedings of the National Academy of Sciences of the United States of America, 93 (18), 9827-9832. doi: 10.1073/pnas.93.18.9827
Sweeney, Neal J., Klemm, Per, McCormick, Beth A., Moller-Nielsen, Eva, Utley, Maryjane, Schembri, Mark A., Laux, David C. and Cohen, Paul S. (1996). The Escherichia coli K-12 gntP gene allows E-coli F-18 to occupy a distinct nutritional niche in the streptomycin-treated mouse large intestine. Infection and Immunity, 64 (9), 3497-3503. doi: 10.1128/IAI.64.9.3497-3503.1996
Schembri, Mark A., Pallesen, Lars, Connell, Hugh, Hasty, David L. and Klemm, Per (1996). Linker insertion analysis of the FimH adhesin of type 1 fimbriae in an Escherichia coli fimH-null background. FEMS Microbiology Letters, 137 (2-3), 257-263. doi: 10.1111/j.1574-6968.1996.tb08115.x
Lambert, J.R., Lin, S.K., Sievert, W., Nicholson, L., Schembri, M. and Guest, C. (1995). High prevalence of helicobacter-pylori antibodies in an institutionalized population: Evidence for person-to-person transmission. American Journal of Gastroenterology, 90 (12), 2167-2171.
Schembri, Mark A., Woods, Alan A., Bayly, Ronald C. and Davies, John K. (1995). Identification of a 13-kDa protein associated with the polyhydroxyalkanoic acid granules from Acinetobacter spp.. FEMS Microbiology Letters, 133 (3), 277-283. doi: 10.1111/j.1574-6968.1995.tb07897.x
Schembri, Mark A., Bayly, Ronald C. and Davies, John K. (1995). Phosphate concentration regulates transcription of the Acinetobacter polyhydroxyalkanoic acid biosynthetic genes. Journal of Bacteriology, 177 (15), 4501-4507. doi: 10.1128/jb.177.15.4501-4507.1995
Lin, Shao K., Lambert, John R., Schembri, Mark A., Nicholson, Lesley and Korman, Melvyn G. (1994). Helicobacter pylori prevalence in endoscopy and medical staff. Journal of Gastroenterology and Hepatology, 9 (4), 319-324. doi: 10.1111/j.1440-1746.1994.tb01249.x
Schembri, Mark A., Bayly, Ronald C. and Davies, John K. (1994). Cloning and analysis of the polyhydroxyalkanoic acid synthase gene from an Acinetobacter sp.: Evidence that the gene is both plasmid and chromosomally located. FEMS Microbiology Letters, 118 (1-2), 145-152. doi: 10.1016/0378-1097(94)90610-6
Schembri, M. A. and Lambert, J. R. (1993). Comparison of commercial diagnostic tests for Helicobacter pylori antibodies. Journal of Clinical Microbiology, 31 (10), 2621-2624. doi: 10.1128/JCM.31.10.2621-2624.1993
Tee, Wee, Lambert, John, Smallwood, Richard, Schembri, Mark, Ross, Bruce C. and Dwyer, Brian (1992). Ribotyping of Helicobacter pylori from clinical specimens. Journal of Clinical Microbiology, 30 (6), 1562-1567. doi: 10.1128/JCM.30.6.1562-1567.1992
Lin, S.K., Lambert, J.R., Schembri, M., Nicholson, L., Finlay, M., Wong, C. and Coulepis, A. (1992). A comparison of diagnostic-tests to determine helicobacter-pylori infection. Journal of Gastroenterology and Hepatology, 7 (2), 203-209. doi: 10.1111/j.1440-1746.1992.tb00963.x
Conference Papers
Stocks, C. J., Kapetanovic, R., Bokil, N., Phan, M. -D, Lo, A., Schembri, M. and Sweet, M. J. (2016). The role of zinc in macrophage antimicrobial responses. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200
Chen, Z., Bates, L. J., Ognenovska, K., McIver, C., Phan, M., Peters, K. M., Moore, K. H. and Schembri, M. (2016). Antibiotic resistance/16S rRNA analysis of bacterial isolates in women with recurrent urinary tract infections and detrusor overactivity. Annual Meeting of the International Continence Society (ICS), Tokyo, Japan, 13-16 September 2016. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/nau.23074
Vance, Megan, Mahony, Timothy, Easton, Donna, Alikhan, Nabil, Beatson, Scott, Schembri, Mark and Cobbold, Rowland (2014). Inoculation of cattle with novel Escherichia coli antigens reduces enteric colonisation by enterohaemorrhagic E. coli O26. Australian Society for Microbiology Annual Scientific Meeting, Melbourne, VIC, Australia, 5 - 9 July 2014.
Wang, Jack T.H., Daly, Joshua N., Willner, Dana L., Patil, Jayee, Hall, Roy, Tyson, Gene W., Hugenholtz, Philip and Schembri, Mark A. (2014). Embedding Undergraduate Research throughout Microbiology Majors. ASM Conference for Undergraduate Educators, Danvers, MA United States, 15-18 May 2014.
Cheng, Y., Chen, Z., Allen, W., Mukerjee, C., Varettas, K., Mansfield, K. J., Schembri, M. A. and Moore, K. H. (2014). Bacterial Filaments Are More Common in Detrusor Overactivity Than Controls: Evidence for Intracellular Bacterial Invasion of Urothelial Cells. 2014 AUGS-IUGA Scientific Meeting, Washington DC, United States, 22-26 July 2014. London, United Kingdom: Springer U K. doi: 10.1007/s00192-014-2429-3
Wang, Jack T. H., Daly, Joshua, Patil, Jayee, Hall, Roy A., Schembri, Mark A., Tyson, Gene W. and Hugenholtz, Philip (2013). Do you kiss your mother with that mouth? An inquiry-driven microbiology undergraduate research experience into the human oral microbiome. Australian Conference on Science and Mathematics Education, Canberra, ACT, Australia, 19 - 21 September 2013.
Thompson, M. F., Gibson, J. S., Mills, P. C., Schembri, M. A., Platell, J. L. and Trott, D. J. (2012). Asymptomatic bacteriuria Escherichia coli strain 83972 in competition with emerging, highly virulent multi-drug resistant Escherichia coli strains in canine urine. 2012 ACVIM Forum, New Orleans, Louisiana, United States, May 30 – June 2 2012. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1111/j.1939-1676.2012.00937.x
Thompson, M. F., Gibson, J. S., Mills, P. C., Schembri, M. A., Platell, J. l. and Trott, D. J. (2012). Asymptomatic bacteriuria Escherichia coli strain 83972 in competition with emerging, highly virulent multi-drug resistant Escherichia coli strains in canine urine. Australian and New Zealand College of Veterinary Scientists Science Week, Gold Coast, Australia, 28-30 June 2012. Sydney, Australia: Australian and New Zealand College of Veterinary Scientists.
Wang, Jack, Hall, Roy and Schembri, Mark (2012). Constructively aligning assessment and feedback - a way forward for integrating SOTL theory and practice in large-scale undergraduate classrooms. 9th Annual International Society for the Scholarship of Teaching and Learning Conference (ISSOTL12), Hamilton, ON, Canada, 24-27 October 2012.
Wang, Jack T. H., Schembri, Mark A. and Fuerst, John A. (2012). How do we embed research into Microbiology Education? A case study in immersive undergraduate research experiences. Australian Society for Microbiology Annual Scientific Meeting (ASM2012), Brisbane, Australia, 1-4 July 2012.
Sweet, M. J., Schroder, K., Irvine, K. M., Taylor, M., Bokil, N. J., Broomfield, S., Schembri, M. A., Stacey, K. J. and Hume, D. A. (2012). Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse. European Congress of Immunology, Glasgow, Scotland, 5-8 September 2012. Oxford, United Kingdom: Wiley-Blackwell. doi: 10.1111/imm.12002
Mansfield, K., Moore, K. H., Cheng, Y. and Schembri, M. (2012). Effect of Escherichia coli lipopolysaccharide on stretch-induced ATP release from cultured urothelial cells. 42nd Annual Meeting of the International-Continence-Society (ICS), Beijing, China, 15-19 October 2012. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/nau.22287
Wang, J. T. H., Schembri, M. A., Ramakrishna, M., Sagulenko, E. and Fuerst, J. A. (2011). Undergraduate research experiences: A case study in promoting student engagement through authentic scientific enquiry. Australian Conference on Science and Mathematics Education, University of Melbourne, Melbourne, Australia, 28/9/2011 - 30/9/2011.
Thompson, M. F., Mills, P. C., Schembri, M. A. and Trott, D. J. (2011). A modified three-dose inoculation protocol for colonisation of the canine urinary tract with the asymptomatic bacteriuria Escherichia coli strain 83972. Australian College of Veterinary Scientists College Science Week, Gold Coast, QLD, Australia, 30 June- 2 July 2011. Sydney , Australia:
Wang, J. T. H., Schembri, M. A. and Fuerst, J. A. (2011). Developing professional research practice in students through undergraduate research experiences. Higher Education Research and Development (HERDSA 2011), Gold Coast , QLD, Australia, 4-7 July 2011.
Thompson, M.F., Mills, P.C., Schembri, M.A. and Trott, D.J. (2011). A modified three-dose inoculation protocol for colonisation of the canine urinary tract with the asymptomatic bacteriuria Escherichia coli strain 83972. Australian College of Veterinary Scientists - Science Week 2011, Gold Coast, QLD, Australia, 30 June- 2 July. Sydney, NSW, Australia:
Thompson, Mary f., Seton, Erica J., Schembri, Mark A., Mills, Paul C. and Trott, Darren J. (2009). A single bladder inoculation with asymptomatic bacteriuria (ABU) strain Escherichia coli 83972 does not achieve persistent bacteriuria in normal dogs. Australian and New Zealand College of Veterinary Scientists Science Week, Surfers Paradise, Gold Coast, Australia, 2-4 July 2009. Brisbane, Qld, Australia: ANZCVS.
Wullt, B., Bergsten, G., Schembri, M. A., Leijonhufvud, I. and Svanborg, C. (2007). E. coli virulence factors; The role of the type 1 fimbriae for host response induction in the human urinary tract. 22nd Annual Congress of the European Association of Urology, Berlin, Germany, 21-24 March 2007. Amsterdam, Netherlands: Elsevier Science. doi: 10.1016/S1569-9056(07)60003-7
Klemm, P., Schembri, M. and Hasty, D. L. (1996). The FIMH protein of type 1 fimbriae - an adaptable adhesin. Bat-Sheva Seminar on Towards Anti-Adhesion Therapy of Microbial Infectious Diseases, Ichron Yaakov, Israel, 25 February - 1 March 1996. New York, United States: Springer.
Connell, H., Agace, W., Hedlund, M., Klemm, P., Shembri, M. and Svanborg, C. (1996). Fimbriae-mediated adherence induces mucosal inflammation and bacterial clearance: consequences for anti-adhesion therapy. Bat-Sheva Seminar on Towards Anti-Adhesion Therapy of Microbial Infectious Diseases, Ichron Yaakov, Israel, 25 February - 1 March 1996. New York, United States: Springer.
Bayly, R. C., Duncan, A., May, J. W., Schembri, M., Semertjis, A., Vasiliadis, G. and Raper, W. G. C. (1991). Microbiological and genetic aspects of the synthesis of polyphosphate by species of Acinetobacter. 15Th Biennial Conf of the International Assoc On Water Pollution Research and Control, Kyoto, Japan, 29 July-3 August 1990. London, United Kingdom: IWA Publishing. doi: 10.2166/wst.1991.0525
Preprints
White, Rhys T., Ashcroft, Melinda A., Bauer, Michelle J., Bell, Jan, Butkiewicz, Dominika, Álvarez-Fraga, Laura, Gibson, Justine S., Kidsley, Amanda K., Mollinger, Joanne L., Peters, Kate M., Phan, Duy, Roberts, Leah W., Rogers, Benjamin, Schembri, Mark, Trott, Darren J., Turnidge, John, Forde, Brian M. and Beatson, Scott A. (2024). The complete genome sequence of five pre-2013 Escherichia coli sequence type (ST)1193 strains reveals insights into an emerging pathogen.. doi: 10.1099/acmi.0.000894.v2
Ashcroft, Melinda M., Forde, Brian M., Phan, Minh-Duy, Peters, Kate M., Roberts, Leah W., Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Paterson, David L., Walsh, Timothy R., Schembri, Mark A. and Beatson, Scott A. (2020). Strain and lineage-level methylome heterogeneity in the multi-drug resistant pathogenic Escherichia coli ST101 clone. doi: 10.1101/2020.06.07.138552
Ashcroft, Melinda M., Forde, Brian M., Phan, Minh-Duy, Peters, Kate M., Henderson, Andrew, Hancock, Steven J., Roberts, Leah W., White, Rhys T., Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Paterson, David L., Walsh, Timothy R., Schembri, Mark A. and Beatson, Scott A. (2020). Genomic characterisation and context of the blaNDM-1 carbapenemase in Escherichia coli ST101. doi: 10.1101/860726